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Molecular Aspects of Breast Cancer Metastasis to the Brain
Joint Authors
Saunus, Jodi M.
Lakhani, Sunil R.
Momeny, Majid
Simpson, Peter T.
Da Silva, Leonard
Source
Genetics Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Our knowledge of the biology underlying the development of brain metastases (BM) from breast cancer has improved over the last decade due to large clinical epidemiological studies, animal models of metastasis, and the use of high-resolution gene expression profiling technologies.
However, there are still major gaps in our understanding of the mechanisms utilized by breast cancer cells to colonize the brain microenvironment, thus our arsenal of therapies remains relatively nonspecific, and the prognosis for breast cancer patients with BM remains poor.
Additional insights into these mechanisms are necessary to facilitate the development of new preventive and curative therapeutic regimens to block this fatal disease.
This paper aims to provide a general overview for the readers of what has been achieved in this field of research and its translation into clinical practice to date and to highlight exciting new areas of research that promise to inform the development of new targeted therapies for BM.
American Psychological Association (APA)
Saunus, Jodi M.& Momeny, Majid& Simpson, Peter T.& Lakhani, Sunil R.& Da Silva, Leonard. 2011. Molecular Aspects of Breast Cancer Metastasis to the Brain. Genetics Research International،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-455565
Modern Language Association (MLA)
Saunus, Jodi M.…[et al.]. Molecular Aspects of Breast Cancer Metastasis to the Brain. Genetics Research International No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-455565
American Medical Association (AMA)
Saunus, Jodi M.& Momeny, Majid& Simpson, Peter T.& Lakhani, Sunil R.& Da Silva, Leonard. Molecular Aspects of Breast Cancer Metastasis to the Brain. Genetics Research International. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-455565
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455565