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Male and Couple Fertility Impairment due to HPV-DNA Sperm Infection : Update on Molecular Mechanism and Clinical Impact—Systematic Review
Joint Authors
Gangemi, Michele
Noventa, Marco
Ferrari, Emanuele
Nardelli, Giovanni Battista
Ferrari, Bruno
Patrelli, Tito Silvio
Gizzo, Salvatore
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-25
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Recent evidences identify Human Papillomavirus (HPV) sperm infection as a possible cause of male and couple infertility.
It acts through different mechanisms at various steps of human conception and early gestational development.
We performed a systematic review to assess the role of HPV semen infection on male and couple infertility.
Analysis of available and eligible data does not permit us to fund clear evidences about clinical impact of HPV infection on fertility, although sperm parameters impairment is the most widely recognized effect.
Regarding biomolecular implications, the available data are often conflicting.
More studies are required to define the role of HPV sperm infection in clinical practice.
The great majority of evidences are obtained by in vitro studies and this fact represents a limitation for the clinical management of HPVDNA sperm infection.
Understanding the biological significance of HPV-DNA semen infection could permit us to explain most of the idiopathic male and couple infertility, leading to a better management of infertile men and a better timing for sperm banking storage before ART cycles.
American Psychological Association (APA)
Gizzo, Salvatore& Ferrari, Bruno& Noventa, Marco& Ferrari, Emanuele& Patrelli, Tito Silvio& Gangemi, Michele…[et al.]. 2014. Male and Couple Fertility Impairment due to HPV-DNA Sperm Infection : Update on Molecular Mechanism and Clinical Impact—Systematic Review. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-455665
Modern Language Association (MLA)
Gizzo, Salvatore…[et al.]. Male and Couple Fertility Impairment due to HPV-DNA Sperm Infection : Update on Molecular Mechanism and Clinical Impact—Systematic Review. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-455665
American Medical Association (AMA)
Gizzo, Salvatore& Ferrari, Bruno& Noventa, Marco& Ferrari, Emanuele& Patrelli, Tito Silvio& Gangemi, Michele…[et al.]. Male and Couple Fertility Impairment due to HPV-DNA Sperm Infection : Update on Molecular Mechanism and Clinical Impact—Systematic Review. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-455665
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455665