Research on Influences of Transient High IOP during LASIK on Retinal Functions and Ultrastructure
Joint Authors
Ai, Yude
Niu, Chunmei
Guan, Wenying
Zhao, Haixia
Qin, Liru
Li, Xiaoling
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
To study the influences of transient high intraocular pressure(IOP) during LASIK on retinal functions and ultrastructure.
Methods.
Thirty-two New Zealand white rabbits were randomly divided into normal control, experimental control, negative suction 20 s and negative suction 3 min groups.
The experimental control group was treated only by laser.
Rabbit eyes received suction for different periods of time (20 s, 3 min) by negative pressure generator in different groups.
The changes of neuro-optic and retinal ultrastructure were observed under electron and light microscopes; retinal neurofunctional changes were observed with flash-visual evoked potential (F-VEP) and flash-electroreinogram (F-ERG).
Results.
There was no obvious change in optic nerve, retina, ERG a-wave and b-wave in normal control and experimental control groups.
There were slight changes in tissues of optic nerve and retina at various times of suction 20 s compared with control group, and a sharp change in suction 3 min group within 14d after operation, but these changes recovered at 28d .
Amplitude of ERG b-wave observed at different time will decrease with suction periods prolonged.
It can recover to normal level with the prolonged recovery periods.
Amplitude and incubation period of ERG a-wave and VEP-P did not change significantly after different duration of suction.
Conclusions.
The transient high IOP during LASIK might have influence on retinal function and ultrastructure, but these changes were reversible.
American Psychological Association (APA)
Zhao, Haixia& Ai, Yude& Niu, Chunmei& Guan, Wenying& Li, Xiaoling& Qin, Liru. 2010. Research on Influences of Transient High IOP during LASIK on Retinal Functions and Ultrastructure. Journal of Ophthalmology،Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-455691
Modern Language Association (MLA)
Zhao, Haixia…[et al.]. Research on Influences of Transient High IOP during LASIK on Retinal Functions and Ultrastructure. Journal of Ophthalmology No. 2009 (2009), pp.1-5.
https://search.emarefa.net/detail/BIM-455691
American Medical Association (AMA)
Zhao, Haixia& Ai, Yude& Niu, Chunmei& Guan, Wenying& Li, Xiaoling& Qin, Liru. Research on Influences of Transient High IOP during LASIK on Retinal Functions and Ultrastructure. Journal of Ophthalmology. 2010. Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-455691
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455691