Syntactic Comprehension in Patients with Amyotrophic Lateral Sclerosis
Joint Authors
Yukimoto, Yumi
Fukuda, Michinari
Ogino, Mieko
Ishizaka, Ikuyo
Yasuda, Nao
Hata, Wakana
Yoshizawa, Kentarou
Higashikawa, Mari
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Recent neuropsychological studies of patients with amyotrophic lateral sclerosis (ALS) have demonstrated that some patients have aphasic symptoms, including impaired syntactic comprehension.
However, it is not known if syntactic comprehension disorder is related to executive and visuospatial dysfunction.
In this study, we evaluated syntactic comprehension using the Syntax Test for Aphasia (STA) auditory comprehension task, frontal executive function using the Frontal Assessment Battery (FAB), visuospatial function using Raven’s Coloured Progressive Matrices (RCPM), and dementia using the Hasegawa Dementia Scale-Revised (HDS-R) in 25 patients with ALS.
Of the 25 patients, 18 (72%) had syntactic comprehension disorder (STA score < IV), nine (36%) had frontal executive dysfunction (FAB score < 14), six (24%) had visuospatial dysfunction (RCPM score < 24), and none had dementia (HDS-R score < 20).
Nine of the 18 patients with syntactic comprehension disorder (50%) passed the FAB and RCPM.
Although sample size was small, these patients had a low STA score but normal FAB and RCPM score.
All patients with bulbar onset ALS had syntactic comprehension disorder.
These results indicate that it might be necessary to assess syntactic comprehension in patients with bulbar onset ALS.
The implications of these findings are discussed in relation to the pathological continuum of ALS.
American Psychological Association (APA)
Yoshizawa, Kentarou& Yasuda, Nao& Fukuda, Michinari& Yukimoto, Yumi& Ogino, Mieko& Hata, Wakana…[et al.]. 2014. Syntactic Comprehension in Patients with Amyotrophic Lateral Sclerosis. Behavioural Neurology،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-455698
Modern Language Association (MLA)
Yoshizawa, Kentarou…[et al.]. Syntactic Comprehension in Patients with Amyotrophic Lateral Sclerosis. Behavioural Neurology No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-455698
American Medical Association (AMA)
Yoshizawa, Kentarou& Yasuda, Nao& Fukuda, Michinari& Yukimoto, Yumi& Ogino, Mieko& Hata, Wakana…[et al.]. Syntactic Comprehension in Patients with Amyotrophic Lateral Sclerosis. Behavioural Neurology. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-455698
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455698