De Novo Balanced Translocation t (7;16) (p22.1; p11.2) Associated with Autistic Disorder
Joint Authors
Ben Jemaa, Lamia
Helayem, M. Béchir
Daoud, Hussein
Bayou, Nadia
Briault, Sylvain
Belhadj, Ahlem
Zemni, Ramzi
M'rad, Ridha
Chaabouni, Habiba
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-04-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The high incidence of de novo chromosomal aberrations in a population of persons with autism suggests a causal relationship between certain chromosomal aberrations and the occurrence of isolated idiopathic autism.
We report on the clinical and cytogenetic findings in a male patient with autism, no physical abnormalities and a de novo balanced (7;16)(p22.1;p16.2) translocation.
G-banded chromosomes and fluorescent in situ hybridization (FISH) were used to examine the patient's karyotype as well as his parents'.
FISH with specific RP11-BAC clones mapping near 7p22.1 and 16p11.2 was used to refine the location of the breakpoints.
This is, in the best of our knowledge, the first report of an individual with autism and this specific chromosomal aberration.
American Psychological Association (APA)
Bayou, Nadia& M'rad, Ridha& Belhadj, Ahlem& Daoud, Hussein& Ben Jemaa, Lamia& Zemni, Ramzi…[et al.]. 2008. De Novo Balanced Translocation t (7;16) (p22.1; p11.2) Associated with Autistic Disorder. Journal of Biomedicine and Biotechnology،Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-455848
Modern Language Association (MLA)
Bayou, Nadia…[et al.]. De Novo Balanced Translocation t (7;16) (p22.1; p11.2) Associated with Autistic Disorder. Journal of Biomedicine and Biotechnology No. 2008 (2008), pp.1-5.
https://search.emarefa.net/detail/BIM-455848
American Medical Association (AMA)
Bayou, Nadia& M'rad, Ridha& Belhadj, Ahlem& Daoud, Hussein& Ben Jemaa, Lamia& Zemni, Ramzi…[et al.]. De Novo Balanced Translocation t (7;16) (p22.1; p11.2) Associated with Autistic Disorder. Journal of Biomedicine and Biotechnology. 2008. Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-455848
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455848
