Validated RP-HPLC Method for the Determination of Buspirone in Pharmaceutical Formulations
Joint Authors
Nagendrakumar, A. V. D.
Maiti, Sushanta
Raja, Guttikonda
Basaveswara Rao, M. V.
Source
Chromatography Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-28
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A simple, selective, linear, precise, and accurate RP-HPLC method was developed and validated for the rapid assay of the Buspirone in tablet dosage form.
Isocratic elution at a flow rate of 1.0 mL/min was employed on a symmetry C18 (250×4.6 mm, 5 μm in particle size) at ambient temperature.
The mobile phase consisted of water : acetonitrile : methanol 45 : 35 : 20(V/V).
The UV detection wavelength was 210 nm, and 20 μL sample was injected.
The retention time for the Buspirone was 7.057 min.
The percentage RSD for precision and accuracy of the method was found to be less than 2%.
The method was validated as per the ICH guidelines.
The method can be successfully applied for the routine analysis of Buspirone in tablet dosage form.
American Psychological Association (APA)
Basaveswara Rao, M. V.& Nagendrakumar, A. V. D.& Maiti, Sushanta& Raja, Guttikonda. 2011. Validated RP-HPLC Method for the Determination of Buspirone in Pharmaceutical Formulations. Chromatography Research International،Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-455896
Modern Language Association (MLA)
Basaveswara Rao, M. V.…[et al.]. Validated RP-HPLC Method for the Determination of Buspirone in Pharmaceutical Formulations. Chromatography Research International No. 2011 (2011), pp.1-3.
https://search.emarefa.net/detail/BIM-455896
American Medical Association (AMA)
Basaveswara Rao, M. V.& Nagendrakumar, A. V. D.& Maiti, Sushanta& Raja, Guttikonda. Validated RP-HPLC Method for the Determination of Buspirone in Pharmaceutical Formulations. Chromatography Research International. 2011. Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-455896
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455896