Vascular Damage in Kidney Disease : Beyond Hypertension
Joint Authors
Pecoits-Filho, Roberto
Stinghen, Andréa E. M.
Source
International Journal of Hypertension
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Chronic kidney disease (CKD) is highly prevalent and a multiplier of cardiovascular disease (CVD) and cannot be completely explained by traditional Framinghan risk factors.
Consequently, greater emphasis has been placed in nontraditional risk factors, such as inflammation, endothelial dysfunction, sympathetic overactivation, protein-energy wasting oxidative stress, vascular calcification, and volume overload.
The accumulation of uremic toxins (and the involvement of genetic factors) is responsible for many of the clinical consequences of a condition known as uremia.
In this brief paper, we discuss mechanisms involved in the vascular damage of CKD patients, aiming to point out that important factors beyond hypertension are largely responsible for endothelial activation and increased CVD risk, with potential impact on risk stratification and development of novel therapeutic options.
American Psychological Association (APA)
Stinghen, Andréa E. M.& Pecoits-Filho, Roberto. 2011. Vascular Damage in Kidney Disease : Beyond Hypertension. International Journal of Hypertension،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-455917
Modern Language Association (MLA)
Stinghen, Andréa E. M.& Pecoits-Filho, Roberto. Vascular Damage in Kidney Disease : Beyond Hypertension. International Journal of Hypertension No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-455917
American Medical Association (AMA)
Stinghen, Andréa E. M.& Pecoits-Filho, Roberto. Vascular Damage in Kidney Disease : Beyond Hypertension. International Journal of Hypertension. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-455917
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455917