![](/images/graphics-bg.png)
Drug Resistance among Pulmonary Tuberculosis Patients in Calabar, Nigeria
Joint Authors
Habib, Abdulrazak
Ameh, Soter
Umoh, Victor Aniedi
Lawson, Lovett
Ansa, Victor
Otu, Akaninyene Asuquo
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
This study aimed to determine the pattern of drug susceptibility to first-line drugs among pulmonary TB patients in two hospitals in Calabar, Nigeria.
Methods.
This was a descriptive cross-sectional study carried out between February 2011 and April 2012.
Sputum samples from consecutive TB patients in Calabar were subjected to culture on Lowenstein-Jensen (LJ) slopes followed by drug susceptibility testing (DST).
The DST was performed on LJ medium by the proportion method.
Results.
Forty-two of the 100 Mycobacterium tuberculosis strains were found to be resistant to at least one drug.
Resistance to only one drug (monoresistance) was found in 17 patients.
No strains with monoresistance to rifampicin were found.
Resistance to two drugs was found in 22 patients, while one patient was resistant to both three and four drugs.
MDR TB was seen in 4% (4/100).
The independent variables of HIV serology and sex were not significantly associated with resistance (P>0.05).
Conclusion.
There was a high prevalence of anti-TB drug resistance in Calabar.
American Psychological Association (APA)
Otu, Akaninyene Asuquo& Umoh, Victor Aniedi& Habib, Abdulrazak& Ameh, Soter& Lawson, Lovett& Ansa, Victor. 2013. Drug Resistance among Pulmonary Tuberculosis Patients in Calabar, Nigeria. Pulmonary Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-456039
Modern Language Association (MLA)
Otu, Akaninyene Asuquo…[et al.]. Drug Resistance among Pulmonary Tuberculosis Patients in Calabar, Nigeria. Pulmonary Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-456039
American Medical Association (AMA)
Otu, Akaninyene Asuquo& Umoh, Victor Aniedi& Habib, Abdulrazak& Ameh, Soter& Lawson, Lovett& Ansa, Victor. Drug Resistance among Pulmonary Tuberculosis Patients in Calabar, Nigeria. Pulmonary Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-456039
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456039