Acylated and Desacylated Ghrelin, Preptin, Leptin, and Nesfatin-1 Peptide Changes Related to the Body Mass Index
Joint Authors
Aksoy, Aziz
Sahin, İbrahim
Timurkan, Mustafa
Aydin, Suleyman
Citil, Cihan
Ozkan, Yusuf
Catak, Zekiye
Timurkan, Esra Suay
Kalayci, Mehmet
Yilmaz, Musa
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
This study examines the levels of acylated and desacylated ghrelin, preptin, leptin, and nesfatin-1 peptide changes related to the body mass index (BMI).
The subjects were allocated to 5 groups depending on their BMIs as follows: Group I (BMI <18.5 kg/m2); Group II (BMI 18.5–24.9 kg/m2); Group III (BMI 25–29.9 kg/m2); Group IV (BMI 30–39.9 kg/m2); Group V (BMI >40 kg/m2).
Serum acylated and desacylated ghrelin, preptin, and leptin levels were measured by the enzyme-linked immunosorbent assay (ELISA) and nesfatin-1 was measured by the enzyme immunoassay (EIA).
Desacylated ghrelin levels showed a gradual and statistically significant drop from Group I to Group V, while preptin and leptin levels exhibited a gradual and significant increase from Group I to Group IV.
Serum nesfatin-1 levels gradually, but not significantly, increased from Group I to Group III and showed a significant decrease in Groups IV and V.
In conclusion, leptin, preptin, and acylated ghrelin (AG) levels increased with higher BMI, whereas desacylated ghrelin (DAG) decreased and nesfatin-1 showed no clear relationship to BMI.
American Psychological Association (APA)
Ozkan, Yusuf& Timurkan, Esra Suay& Aydin, Suleyman& Sahin, İbrahim& Timurkan, Mustafa& Citil, Cihan…[et al.]. 2013. Acylated and Desacylated Ghrelin, Preptin, Leptin, and Nesfatin-1 Peptide Changes Related to the Body Mass Index. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-456120
Modern Language Association (MLA)
Ozkan, Yusuf…[et al.]. Acylated and Desacylated Ghrelin, Preptin, Leptin, and Nesfatin-1 Peptide Changes Related to the Body Mass Index. International Journal of Endocrinology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-456120
American Medical Association (AMA)
Ozkan, Yusuf& Timurkan, Esra Suay& Aydin, Suleyman& Sahin, İbrahim& Timurkan, Mustafa& Citil, Cihan…[et al.]. Acylated and Desacylated Ghrelin, Preptin, Leptin, and Nesfatin-1 Peptide Changes Related to the Body Mass Index. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-456120
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456120