The Role of Cell Surface Architecture of Lactobacilli in Host-Microbe Interactions in the Gastrointestinal Tract
Joint Authors
Anderson, Rachel C.
Moughan, Paul J.
Sengupta, Ranjita
Altermann, Eric
Roy, Nicole C.
McNabb, Warren C.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-13
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Lactobacillus species can exert health promoting effects in the gastrointestinal tract (GIT) through many mechanisms, which include pathogen inhibition, maintenance of microbial balance, immunomodulation, and enhancement of the epithelial barrier function.
Different species of the genus Lactobacillus can evoke different responses in the host, and not all strains of the same species can be considered beneficial.
Strain variations may be related to diversity of the cell surface architecture of lactobacilli and the bacteria's ability to express certain surface components or secrete specific compounds in response to the host environment.
Lactobacilli are known to modify their surface structures in response to stress factors such as bile and low pH, and these adaptations may help their survival in the face of harsh environmental conditions encountered in the GIT.
In recent years, multiple cell surface-associated molecules have been implicated in the adherence of lactobacilli to the GIT lining, immunomodulation, and protective effects on intestinal epithelial barrier function.
Identification of the relevant bacterial ligands and their host receptors is imperative for a better understanding of the mechanisms through which lactobacilli exert their beneficial effects on human health.
American Psychological Association (APA)
Sengupta, Ranjita& Altermann, Eric& Anderson, Rachel C.& McNabb, Warren C.& Moughan, Paul J.& Roy, Nicole C.. 2013. The Role of Cell Surface Architecture of Lactobacilli in Host-Microbe Interactions in the Gastrointestinal Tract. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-456285
Modern Language Association (MLA)
Sengupta, Ranjita…[et al.]. The Role of Cell Surface Architecture of Lactobacilli in Host-Microbe Interactions in the Gastrointestinal Tract. Mediators of Inflammation No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-456285
American Medical Association (AMA)
Sengupta, Ranjita& Altermann, Eric& Anderson, Rachel C.& McNabb, Warren C.& Moughan, Paul J.& Roy, Nicole C.. The Role of Cell Surface Architecture of Lactobacilli in Host-Microbe Interactions in the Gastrointestinal Tract. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-456285
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456285