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Rhabdomyosarcoma with Pseudolipoblasts Arising in Ovarian Carcinosarcoma : A Distinctive Postchemotherapy Morphologic Variant Mimicking Pleomorphic Liposarcoma
Joint Authors
Banerjee, Susana
Thway, Khin
Hazell, Steve
Fisher, Cyril
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We describe a case of ovarian carcinosarcoma occurring in a 60-year-old female.
The neoplasm was excised after neoadjuvant chemotherapy and contained a predominant heterologous pleomorphic rhabdomyosarcomatous component in which there were numerous multivacuolated rhabdomyoblasts that strongly mimicked lipoblasts.
The clear cell variant of rhabdomyosarcoma is rarely documented, but this case shows a highly unusual finding in which the rhabdomyoblasts show the prominent multivacuolation with nuclear indentation characteristic of and indistinguishable from pleomorphic lipoblasts.
This appears to represent a posttreatment phenomenon.
As this finding might conceivably occur in other rhabdomyosarcomas after chemotherapy, we highlight the potential for diagnostic confusion with pleomorphic liposarcoma, which is usually diagnosed by morphology so that immunohistochemistry for muscle markers might not be performed.
American Psychological Association (APA)
Thway, Khin& Hazell, Steve& Banerjee, Susana& Fisher, Cyril. 2014. Rhabdomyosarcoma with Pseudolipoblasts Arising in Ovarian Carcinosarcoma : A Distinctive Postchemotherapy Morphologic Variant Mimicking Pleomorphic Liposarcoma. Case Reports in Pathology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-456359
Modern Language Association (MLA)
Thway, Khin…[et al.]. Rhabdomyosarcoma with Pseudolipoblasts Arising in Ovarian Carcinosarcoma : A Distinctive Postchemotherapy Morphologic Variant Mimicking Pleomorphic Liposarcoma. Case Reports in Pathology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-456359
American Medical Association (AMA)
Thway, Khin& Hazell, Steve& Banerjee, Susana& Fisher, Cyril. Rhabdomyosarcoma with Pseudolipoblasts Arising in Ovarian Carcinosarcoma : A Distinctive Postchemotherapy Morphologic Variant Mimicking Pleomorphic Liposarcoma. Case Reports in Pathology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-456359
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456359