Idiopathic Uveitis and Familial Mediterranean Fever : Is There Any Relationship?
Joint Authors
Hosseini Khotbesara, Mahsa
Yasrebi, Ozra
Salehzadeh, Farhad
Hosseini Khotbesara, Maryam
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-30
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Introduction.
Familial Mediterranean fever (FMF) is an auto-inflammatory disease characterized by attacks of fever and polyserositis.
FMF is often associated with other autoimmune diseases such as rheumatoid arthritis, polyarteritis nodosa (PAN), and Behcet.
Uveitis is an inflammatory process caused by underlying infectious and inflammatory disorders.
This study investigates the probable relationship between idiopathic uveitis and FMF.
Methods.
Patients with idiopathic uveitis were analyzed for the 12 most common MEFV mutations (P369S, F479L, M680I(G/C), M680I(G/A), I692del, M694V, M694I, K695R, V726A, A744S, R761H, E148Q) by a reverse hybridization assay (FMF StripAssay,Vienna lab,Vienna, Austria).
Results.
12 patients with idiopathic uveitis were enrolled in this study.
10 of them were female.
The youngest patient was a 7-year-old child and the oldest was 57.
The most common complaints of patients were blurred vision and then eye redness.
One patient was heterozygous for R761H.
Genetic analysis of the 12 most common MEFV mutations in the patients with idiopathic uveitis didnot have any positive results.
Conclusion.
According to the analysis of the 12 most common MEFV gene mutations, FMF is not an underlying cause of idiopathic uveitis.
On the other hand, uveitis merely could not be the first presentation of FMF.
American Psychological Association (APA)
Salehzadeh, Farhad& Yasrebi, Ozra& Hosseini Khotbesara, Mahsa& Hosseini Khotbesara, Maryam. 2014. Idiopathic Uveitis and Familial Mediterranean Fever : Is There Any Relationship?. Autoimmune Diseases،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-456394
Modern Language Association (MLA)
Salehzadeh, Farhad…[et al.]. Idiopathic Uveitis and Familial Mediterranean Fever : Is There Any Relationship?. Autoimmune Diseases No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-456394
American Medical Association (AMA)
Salehzadeh, Farhad& Yasrebi, Ozra& Hosseini Khotbesara, Mahsa& Hosseini Khotbesara, Maryam. Idiopathic Uveitis and Familial Mediterranean Fever : Is There Any Relationship?. Autoimmune Diseases. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-456394
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456394