Automated White Matter Hyperintensity Detection in Multiple Sclerosis Using 3D T2 FLAIR
Joint Authors
Zhong, Yi
Wang, Ying
Haacke, E. Mark
Utriainen, David
Kang, Yan
Source
International Journal of Biomedical Imaging
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
White matter hyperintensities (WMH) seen on T2WI are a hallmark of multiple sclerosis (MS) as it indicates inflammation associated with the disease.
Automatic detection of the WMH can be valuable in diagnosing and monitoring of treatment effectiveness.
T2 fluid attenuated inversion recovery (FLAIR) MR images provided good contrast between the lesions and other tissue; however the signal intensity of gray matter tissue was close to the lesions in FLAIR images that may cause more false positives in the segment result.
We developed and evaluated a tool for automated WMH detection only using high resolution 3D T2 fluid attenuated inversion recovery (FLAIR) MR images.
We use a high spatial frequency suppression method to reduce the gray matter area signal intensity.
We evaluate our method in 26 MS patients and 26 age matched health controls.
The data from the automated algorithm showed good agreement with that from the manual segmentation.
The linear correlation between these two approaches in comparing WMH volumes was found to be Y=1.04X+1.74 (R2=0.96).
The automated algorithm estimates the number, volume, and category of WMH.
American Psychological Association (APA)
Zhong, Yi& Utriainen, David& Wang, Ying& Kang, Yan& Haacke, E. Mark. 2014. Automated White Matter Hyperintensity Detection in Multiple Sclerosis Using 3D T2 FLAIR. International Journal of Biomedical Imaging،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-456421
Modern Language Association (MLA)
Zhong, Yi…[et al.]. Automated White Matter Hyperintensity Detection in Multiple Sclerosis Using 3D T2 FLAIR. International Journal of Biomedical Imaging No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-456421
American Medical Association (AMA)
Zhong, Yi& Utriainen, David& Wang, Ying& Kang, Yan& Haacke, E. Mark. Automated White Matter Hyperintensity Detection in Multiple Sclerosis Using 3D T2 FLAIR. International Journal of Biomedical Imaging. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-456421
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456421