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Blends of Thermoplastic Polyurethane and Polydimethylsiloxane Rubber : Assessment of Biocompatibility and Suture Holding Strength of Membranes
Joint Authors
Parameswar, Ramesh
Nando, G. B.
Rajan, Krishna Prasad
al-Ghamdi, Ahmed
Source
International Journal of Biomaterials
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
In the present investigation, a compatibilized blend of thermoplastic polyurethane (TPU) and polydimethylsiloxane (PDMS) is prepared by using copolymer of ethylene and methyl acrylate (EMA) as a reactive compatibilizer.
Detailed in vitro biocompatibility studies were carried out for this compatibilized blend and the material was found noncytotoxic towards L929 mouse fibroblast subcutaneous connective tissue cell line.
Microporosity was created on the surface of membranes prepared from the blend material by adopting the crazing mechanism.
Cell proliferation and growth studies on the membranes surface showed that the microporous surface favoured ingrowth of the cells compared with a nonmicroporous surface.
Suture holding strength studies indicate that the microporous membranes have enough strength to withstand the cutting and tearing forces through the suture hole.
This blend material could be evaluated further to find its suitability in various implant applications.
American Psychological Association (APA)
Rajan, Krishna Prasad& al-Ghamdi, Ahmed& Parameswar, Ramesh& Nando, G. B.. 2013. Blends of Thermoplastic Polyurethane and Polydimethylsiloxane Rubber : Assessment of Biocompatibility and Suture Holding Strength of Membranes. International Journal of Biomaterials،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-456562
Modern Language Association (MLA)
Rajan, Krishna Prasad…[et al.]. Blends of Thermoplastic Polyurethane and Polydimethylsiloxane Rubber : Assessment of Biocompatibility and Suture Holding Strength of Membranes. International Journal of Biomaterials No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-456562
American Medical Association (AMA)
Rajan, Krishna Prasad& al-Ghamdi, Ahmed& Parameswar, Ramesh& Nando, G. B.. Blends of Thermoplastic Polyurethane and Polydimethylsiloxane Rubber : Assessment of Biocompatibility and Suture Holding Strength of Membranes. International Journal of Biomaterials. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-456562
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456562