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Attachment and Proliferation of Human-Adipose-Tissue-Derived Stem Cells on Bioactive GlassPVA Hybrid Scaffolds
Joint Authors
Cavalcanti Zonari, Alessandra Arcoverde
Gomide, Viviane
Breyner, Natalia Martins
de Goes, Alfredo Miranda
Pereira, Marivalda M.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Bioactive glass/polymer hybrids are promising materials for biomedical applications because they combine the bioactivity of bioceramics with the flexibility of polymers.
These advantages may be used in porous scaffolds for tissue-engineering applications.
In previous works, hybrid foams bioactive glass/polyvinyl alcohol (PVA) were prepared by the sol-gel process.
The hybrid foam 50% PVA/50% bioactive glass was chosen in the composition range studied as the scaffold with better compromise in terms of pore structure and mechanical behavior.
The aim of the present study was to evaluate the adhesion, viability, and growth behavior of human-adipose-tissue-derived stem cells on bioactive glass/PVA foams in vitro and their potential as scaffold for application in bone-tissue engineering.
The pore structure of the hybrid samples used in the study was analyzed by microcomputed tomography, showing a modal pore diameter of 284 μm and modal interconnect diameter of 138 μm.
We found that cells are capable of adhesion, proliferation, growth, and ECM production on the scaffolds tested.
The results show that the hybrid bioactive glass/PVA is a promising material for bone repair, providing a good environment for the adhesion and proliferation of human-adipose-tissue-derived stem cells in vitro.
American Psychological Association (APA)
Gomide, Viviane& Cavalcanti Zonari, Alessandra Arcoverde& Breyner, Natalia Martins& de Goes, Alfredo Miranda& Pereira, Marivalda M.. 2011. Attachment and Proliferation of Human-Adipose-Tissue-Derived Stem Cells on Bioactive GlassPVA Hybrid Scaffolds. ISRN Materials Science،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-456589
Modern Language Association (MLA)
Gomide, Viviane…[et al.]. Attachment and Proliferation of Human-Adipose-Tissue-Derived Stem Cells on Bioactive GlassPVA Hybrid Scaffolds. ISRN Materials Science No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-456589
American Medical Association (AMA)
Gomide, Viviane& Cavalcanti Zonari, Alessandra Arcoverde& Breyner, Natalia Martins& de Goes, Alfredo Miranda& Pereira, Marivalda M.. Attachment and Proliferation of Human-Adipose-Tissue-Derived Stem Cells on Bioactive GlassPVA Hybrid Scaffolds. ISRN Materials Science. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-456589
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456589