Aminoterminal Pro B-Type Natriuretic Peptide (NT-proBNP) Levels for Monitoring Interventions in Paediatric Cardiac Patients with Stenotic Lesions
Joint Authors
Haas, Nikolaus A.
Filler, Guido
Rauch, Ralf
Welisch, Eva
Norozi, Kambiz
Kleesiek, Knut
Source
International Journal of Pediatrics
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Serum concentration of NT-proBNP correlates well with the severity of cardiac disease in adults.
Few studies have been performed on the applicability of NT-proBNP for monitoring children with congenital heart disease.
Objective.
To assess the potential of NT-proBNP for monitoring the success of interventions in children with stenotic cardiac lesions.
Methods.
NT-proBNP was measured in 42 children aged 1 day to 17 years (y) before and 6 to 12 weeks after surgical or interventional correction of obstructive lesions of the heart.
Comparison is made with the clinical status and echocardiographic data of the child.
Results.
NT-proBNP levels (median 280, range 10–263,000 pg/mL) were above the reference value in all but 6 patients (pts) prior to the intervention.
Higher levels were found in more compromised patients.
The 35 children with clinical improvement after the procedure showed a decline of their NT-proBNP level in all but 4 patients, whose levels remained unchanged.
Five patients with unchanged gradients despite a therapeutic intervention also demonstrated unchanged NT-proBNP levels after the intervention.
Thus, the success rate of the procedure correlated well to clinical and echocardiographic findings.
Conclusion.
NT-proBNP can be used to assess the efficiency of an intervention.
American Psychological Association (APA)
Welisch, Eva& Kleesiek, Knut& Haas, Nikolaus A.& Norozi, Kambiz& Rauch, Ralf& Filler, Guido. 2010. Aminoterminal Pro B-Type Natriuretic Peptide (NT-proBNP) Levels for Monitoring Interventions in Paediatric Cardiac Patients with Stenotic Lesions. International Journal of Pediatrics،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-456622
Modern Language Association (MLA)
Welisch, Eva…[et al.]. Aminoterminal Pro B-Type Natriuretic Peptide (NT-proBNP) Levels for Monitoring Interventions in Paediatric Cardiac Patients with Stenotic Lesions. International Journal of Pediatrics No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-456622
American Medical Association (AMA)
Welisch, Eva& Kleesiek, Knut& Haas, Nikolaus A.& Norozi, Kambiz& Rauch, Ralf& Filler, Guido. Aminoterminal Pro B-Type Natriuretic Peptide (NT-proBNP) Levels for Monitoring Interventions in Paediatric Cardiac Patients with Stenotic Lesions. International Journal of Pediatrics. 2010. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-456622
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456622