Stokes Efficiency of Molecular Motor-Cargo Systems
Joint Authors
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-05-19
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
A molecular motor utilizes chemical free energy to generate a unidirectional motion through the viscous fluid.
In many experimental settings and biological settings, a molecular motor is elastically linked to a cargo.
The stochastic motion of a molecular motor-cargo system is governed by a set of Langevin equations, each corresponding to an individual chemical occupancy state.
The change of chemical occupancy state is modeled by a continuous time discrete space Markov process.
The probability density of a motor-cargo system is governed by a two-dimensional Fokker-Planck equation.
The operation of a molecular motor is dominated by high viscous friction and large thermal fluctuations from surrounding fluid.
The instantaneous velocity of a molecular motor is highly stochastic: the past velocity is quickly damped by the viscous friction and the new velocity is quickly excited by bombardments of surrounding fluid molecules.
Thus, the theory for macroscopic motors should not be applied directly to molecular motors without close examination.
In particular, a molecular motor behaves differently working against a viscous drag than working against a conservative force.
The Stokes efficiency was introduced to measure how efficiently a motor uses chemical free energy to drive against viscous drag.
For a motor without cargo, it was proved that the Stokes efficiency is bounded by 100% [H.
Wang and G.
Oster, (2002)].
Here, we present a proof for the general motor-cargo system.
American Psychological Association (APA)
Wang, Hongyun& Zhou, Hong. 2008. Stokes Efficiency of Molecular Motor-Cargo Systems. Abstract and Applied Analysis،Vol. 2008, no. 2008, pp.1-13.
https://search.emarefa.net/detail/BIM-456659
Modern Language Association (MLA)
Wang, Hongyun& Zhou, Hong. Stokes Efficiency of Molecular Motor-Cargo Systems. Abstract and Applied Analysis No. 2008 (2008), pp.1-13.
https://search.emarefa.net/detail/BIM-456659
American Medical Association (AMA)
Wang, Hongyun& Zhou, Hong. Stokes Efficiency of Molecular Motor-Cargo Systems. Abstract and Applied Analysis. 2008. Vol. 2008, no. 2008, pp.1-13.
https://search.emarefa.net/detail/BIM-456659
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456659