Recent Advancements in Cytotoxic T Lymphocyte Generation Methods Using Carbohydrate-Coated Liposomes
Joint Authors
Yamaguchi, Takashi
Ikehara, Yuzuru
Yamanaka, Masahiro
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Both tumor-specific CD4+ and CD8+ T cells have been identified, and the latter is known as a major effector of adaptive antitumor immune responses.
Optimal antitumor immune responses are considered to require the concomitant activation of both CD8+ and CD4+ T cells and the additional selective activation of CD4+ T cells with helper, but not regulatory function.
As optimal antitumor immune responses are generated by the concomitant activation of both T cell types, it is necessary for vaccine methods involving cytotoxic T-lymphocytes (CTLs) generation to possess a mechanism whereby antigen presenting cells can present administrated exogenous antigens on not only Major histocompatibility complex (MHC) class II, but also MHC class I molecules.
American Psychological Association (APA)
Ikehara, Yuzuru& Yamanaka, Masahiro& Yamaguchi, Takashi. 2010. Recent Advancements in Cytotoxic T Lymphocyte Generation Methods Using Carbohydrate-Coated Liposomes. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-456718
Modern Language Association (MLA)
Ikehara, Yuzuru…[et al.]. Recent Advancements in Cytotoxic T Lymphocyte Generation Methods Using Carbohydrate-Coated Liposomes. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-456718
American Medical Association (AMA)
Ikehara, Yuzuru& Yamanaka, Masahiro& Yamaguchi, Takashi. Recent Advancements in Cytotoxic T Lymphocyte Generation Methods Using Carbohydrate-Coated Liposomes. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-456718
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456718