Prognostic Value of Left Ventricular Diastolic Dysfunction in Patients Undergoing Cardiac Catheterization for Coronary Artery Disease
Joint Authors
Fukuta, Hidekatsu
Kimura, Genjiro
Goto, Toshihiko
Tani, Tomomitsu
Wakami, Kazuaki
Ohte, Nobuyuki
Source
Cardiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We hypothesized that left ventricular (LV) diastolic dysfunction assessed by cardiac catheterization may be associated with increased risk for cardiovascular events.
To test the hypothesis, we assessed diastolic function by cardiac catheterization (relaxation time constant (Tau) and end-diastolic pressure (EDP)) as well as Doppler echocardiography (early diastolic mitral annular velocity (e′) and a ratio of early diastolic mitral inflow to annular velocities (E/e′)) in 222 consecutive patients undergoing cardiac catheterization for coronary artery disease (CAD).
During a followup of 1364 ± 628 days, 5 cardiac deaths and 20 unscheduled cardiovascular hospitalizations were observed.
Among LV diastolic function indices, Tau > 48 ms and e′<5.8 cm/s were each significantly associated with lower rate of survival free of cardiovascular hospitalization.
Even after adjustment for potential confounders (traditional cardiovascular risk factors, the severity of CAD, and cardiovascular medications), the predictive value of Tau > 48 ms and e′<5.8 cm/s remained significant.
No predictive value was observed in EDP, E/e′, or LV ejection fraction.
In conclusion, LV diastolic dysfunction, particularly impaired LV relaxation assessed by both cardiac catheterization and Doppler echocardiography, is independently associated with increased risk for cardiac death or cardiovascular hospitalization in patients with known or suspected CAD.
American Psychological Association (APA)
Fukuta, Hidekatsu& Ohte, Nobuyuki& Wakami, Kazuaki& Goto, Toshihiko& Tani, Tomomitsu& Kimura, Genjiro. 2012. Prognostic Value of Left Ventricular Diastolic Dysfunction in Patients Undergoing Cardiac Catheterization for Coronary Artery Disease. Cardiology Research and Practice،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-456822
Modern Language Association (MLA)
Fukuta, Hidekatsu…[et al.]. Prognostic Value of Left Ventricular Diastolic Dysfunction in Patients Undergoing Cardiac Catheterization for Coronary Artery Disease. Cardiology Research and Practice No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-456822
American Medical Association (AMA)
Fukuta, Hidekatsu& Ohte, Nobuyuki& Wakami, Kazuaki& Goto, Toshihiko& Tani, Tomomitsu& Kimura, Genjiro. Prognostic Value of Left Ventricular Diastolic Dysfunction in Patients Undergoing Cardiac Catheterization for Coronary Artery Disease. Cardiology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-456822
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456822