Morphological Changes in the Suprachiasmatic Nucleus of Aging Female Marmosets (Callithrix jacchus)
Joint Authors
Santos, Jose Ronaldo dos
Engelberth, Rovena Clara G. J.
Nascimento Junior, Expedito S.
Cavalcante, Jeferson S.
Silva, Kayo Diogenes de A.
Gavioli, Elaine Cristina
Soares, Joacil Germano
Azevedo, Carolina V. de M.
Costa, Miriam Stela M. O.
Cavalcante, Judney C.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-02
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The suprachiasmatic nuclei (SCN) are pointed to as the mammals central circadian pacemaker.
Aged animals show internal time disruption possibly caused by morphological and neurochemical changes in SCN components.
Some studies reported changes of neuronal cells and neuroglia in the SCN of rats and nonhuman primates during aging.
The effects of senescence on morphological aspects in SCN are important for understanding some alterations in biological rhythms expression.
Therefore, our aim was to perform a comparative study of the morphological aspects of SCN in adult and aged female marmoset.
Morphometric analysis of SCN was performed using Nissl staining, NeuN-IR, GFAP-IR, and CB-IR.
A significant decrease in the SCN cells staining with Nissl, NeuN, and CB were observed in aged female marmosets compared to adults, while a significant increase in glial cells was found in aged marmosets, thus suggesting compensatory process due to neuronal loss evoked by aging.
American Psychological Association (APA)
Engelberth, Rovena Clara G. J.& Silva, Kayo Diogenes de A.& Azevedo, Carolina V. de M.& Gavioli, Elaine Cristina& Santos, Jose Ronaldo dos& Soares, Joacil Germano…[et al.]. 2014. Morphological Changes in the Suprachiasmatic Nucleus of Aging Female Marmosets (Callithrix jacchus). BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-456834
Modern Language Association (MLA)
Engelberth, Rovena Clara G. J.…[et al.]. Morphological Changes in the Suprachiasmatic Nucleus of Aging Female Marmosets (Callithrix jacchus). BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-456834
American Medical Association (AMA)
Engelberth, Rovena Clara G. J.& Silva, Kayo Diogenes de A.& Azevedo, Carolina V. de M.& Gavioli, Elaine Cristina& Santos, Jose Ronaldo dos& Soares, Joacil Germano…[et al.]. Morphological Changes in the Suprachiasmatic Nucleus of Aging Female Marmosets (Callithrix jacchus). BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-456834
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456834