The Metabolic Syndrome and Biochemical Recurrence following Radical Prostatectomy
Joint Authors
Jankowski, Michelle
Rybicki, Benjamin A.
Neslund-Dudas, Christine
Bock, Cathryn H.
Morgenstern, Hal
Post, Jennifer M.
Beebe-Dimmer, Jennifer L.
Nock, Nora
Rundle, Andrew
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Metabolic syndrome refers to a set of conditions that increases the risk of cardiovascular disease and has been associated with an increased risk of prostate cancer, particularly among African American men.
This study aimed to estimate the association of metabolic syndrome with biochemical recurrence (BCR) in a racially diverse population.
Among 383 radical prostatectomy patients, 67 patients had documented biochemical recurrence.
Hypertension was significantly, positively associated with the rate of BCR (hazard ratio (HR) = 2.1; 95% CI = 1.1, 3.8).
There were distinct racial differences in the prevalence of individual metabolic syndrome components; however, the observed associations with BCR did not differ appreciably by race.
We conclude that hypertension may contribute to a poorer prognosis in surgically treated prostate cancer patients.
Our findings suggest that targeting components of the metabolic syndrome which are potentially modifiable through lifestyle interventions may be a viable strategy to reduce risk of BCR in prostate cancer.
American Psychological Association (APA)
Post, Jennifer M.& Beebe-Dimmer, Jennifer L.& Morgenstern, Hal& Neslund-Dudas, Christine& Bock, Cathryn H.& Nock, Nora…[et al.]. 2011. The Metabolic Syndrome and Biochemical Recurrence following Radical Prostatectomy. Prostate Cancer،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-456918
Modern Language Association (MLA)
Post, Jennifer M.…[et al.]. The Metabolic Syndrome and Biochemical Recurrence following Radical Prostatectomy. Prostate Cancer No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-456918
American Medical Association (AMA)
Post, Jennifer M.& Beebe-Dimmer, Jennifer L.& Morgenstern, Hal& Neslund-Dudas, Christine& Bock, Cathryn H.& Nock, Nora…[et al.]. The Metabolic Syndrome and Biochemical Recurrence following Radical Prostatectomy. Prostate Cancer. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-456918
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456918