Management of the Kidney Transplant Patient with Chronic Hepatitis C Infection
Joint Authors
Tzvetanov, Ivo
Tang, Ignatius Y. S.
Walzer, Natasha
Aggarwal, Nidhi
Benedetti, Enrico
Cotler, Scott J.
Source
International Journal of Nephrology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Chronic Hepatitis C (HCV) infection is an important cause of morbidity and mortality in patients with end-stage renal disease.
Renal transplantation confers a survival advantage in HCV-infected patients.
Renal transplant candidates with serologic evidence of HCV infection should undergo a liver biopsy to assess for fibrosis and cirrhosis.
Patients with Metavir fibrosis score ≤3 and compensated cirrhosis should be evaluated for interferon-based therapy.
Achievement of sustained virological response (SVR) may reduce the risks for both posttransplantation hepatic and extrahepatic complications such as de novo or recurrent glomerulonephritis associated with HCV.
Patients who cannot achieve SVR and have no live kidney donor may be considered for HCV-positive kidneys.
Interferon should be avoided after kidney transplant except for treatment of life-threatening liver injury, such as fibrosing cholestatic hepatitis.
Early detection, prevention, and treatment of complications due to chronic HCV infection may improve the outcomes of kidney transplant recipients with chronic HCV infection.
American Psychological Association (APA)
Tang, Ignatius Y. S.& Walzer, Natasha& Aggarwal, Nidhi& Tzvetanov, Ivo& Cotler, Scott J.& Benedetti, Enrico. 2011. Management of the Kidney Transplant Patient with Chronic Hepatitis C Infection. International Journal of Nephrology،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-456944
Modern Language Association (MLA)
Tang, Ignatius Y. S.…[et al.]. Management of the Kidney Transplant Patient with Chronic Hepatitis C Infection. International Journal of Nephrology No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-456944
American Medical Association (AMA)
Tang, Ignatius Y. S.& Walzer, Natasha& Aggarwal, Nidhi& Tzvetanov, Ivo& Cotler, Scott J.& Benedetti, Enrico. Management of the Kidney Transplant Patient with Chronic Hepatitis C Infection. International Journal of Nephrology. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-456944
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456944