The Effects of Wenxin Keli on P-Wave Dispersion and Maintenance of Sinus Rhythm in Patients with Paroxysmal Atrial Fibrillation : A Meta-Analysis of Randomized Controlled Trials
Joint Authors
Zhang, Zhenpeng
Teng, Fei
Chen, Yu
Chen, Wen
Xing, Yanhui
Nie, Shaoping
Wang, Jie
Shang, Hongcai
Sun, Tao
Yan-Wei, Xing
Gao, Hai
Yong-Hong, Gao
Liu, Xiaoqiu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-04
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
To evaluate the beneficial and adverse effects of Wenxin Keli (WXKL), alone or combined with Western medicine, on P-wave dispersion (Pd) and maintenance of sinus rhythm for the treatment of paroxysmal atrial fibrillation (PAF).
Methods.
Seven major electronic databases were searched to retrieve randomized controlled trials (RCTs) designed to evaluate the clinical effectiveness of WXKL, alone or combined with Western medicine, for PAF, with Pd or maintenance rate of sinus rhythm as the main outcome measure.
The methodological quality of the included studies was assessed using criteria from the Cochrane Handbook for Systematic Review of Interventions, version 5.1.0, and analysed using RevMan 5.1.0 software.
Results.
Fourteen RCTs of WXKL were included.
The methodological quality of the trials was generally evaluated as low.
The results of meta-analysis showed that WXKL, alone or combined with Western medicine, was more effective in Pd and the maintenance of sinus rhythm, compared with no medicine or Western medicine alone, in patients with PAF or PAF complicated by other diseases.
Seven of the trials reported adverse events, indicating that the safety of WXKL is still uncertain.
Conclusions.
WXKL, alone or combined with Western medicine, appears to be more effective in improving Pd as well as maintenance of sinus rhythm in patients with PAF and its complications.
American Psychological Association (APA)
Chen, Yu& Nie, Shaoping& Gao, Hai& Sun, Tao& Liu, Xiaoqiu& Teng, Fei…[et al.]. 2013. The Effects of Wenxin Keli on P-Wave Dispersion and Maintenance of Sinus Rhythm in Patients with Paroxysmal Atrial Fibrillation : A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-456963
Modern Language Association (MLA)
Chen, Yu…[et al.]. The Effects of Wenxin Keli on P-Wave Dispersion and Maintenance of Sinus Rhythm in Patients with Paroxysmal Atrial Fibrillation : A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-456963
American Medical Association (AMA)
Chen, Yu& Nie, Shaoping& Gao, Hai& Sun, Tao& Liu, Xiaoqiu& Teng, Fei…[et al.]. The Effects of Wenxin Keli on P-Wave Dispersion and Maintenance of Sinus Rhythm in Patients with Paroxysmal Atrial Fibrillation : A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-456963
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456963