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Preparation and Characterisation of Highly Loaded Fluorescent Chitosan Nanoparticles
Joint Authors
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Chitosan (CS) nanoparticles have been developed as a versatile drug delivery system to transport drugs, genes, proteins, and peptides into target sites.
Demands on fluorescent nanoparticles have increased recently due to various applications in medical and stem-cell-based researches.
In this study, fluorescent CS nanoparticles were prepared by a mild method, namely, complex coacervation.
Entrapment efficiency of sulforhodamine (SR101) loaded into CS nanoparticles was investigated to evaluate their capacity in incorporating fluorescent molecule.
Particle size of produced fluorescent nanoparticles was in the range of 600–700 nm, and their particle size was highly dependent on the CS molecular weight as well as concentration.
A high entrapment efficiency of SR101 into CS nanoparticles could also be obtained when it was dissolved in methanol.
In conclusion, highly loaded fluorescent CS nanoparticles could be easily prepared using complex coacervation method and therefore can be applied in various medical researches.
American Psychological Association (APA)
Katas, Haliza& Mui Wen, Chan. 2011. Preparation and Characterisation of Highly Loaded Fluorescent Chitosan Nanoparticles. ISRN Pharmaceutics،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-456985
Modern Language Association (MLA)
Katas, Haliza& Mui Wen, Chan. Preparation and Characterisation of Highly Loaded Fluorescent Chitosan Nanoparticles. ISRN Pharmaceutics No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-456985
American Medical Association (AMA)
Katas, Haliza& Mui Wen, Chan. Preparation and Characterisation of Highly Loaded Fluorescent Chitosan Nanoparticles. ISRN Pharmaceutics. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-456985
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-456985