Human Papillomavirus Types 52 and 58 Are Prevalent in Uterine Cervical Squamous Lesions from Japanese Women
Joint Authors
Mizunoe, Tomoya
Toda, Tamaki
Takehara, Kazuhiro
Nishiwaki, Morie
Kawakami, Yosuke
Nishimura, Toshinao
Sakane, Junichi
Taniyama, Kiyomi
Source
Pathology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To estimate the prevalence and genotypes of high-risk human papillomavirus (HPV) focusing HPV 16, 18, 52, and 58 in Japan.
Methods.
Liquid-base cytology specimens were collected from Japanese women (n=11022), aged 14–98.
After classifying cytodiagnosis, specimens were analyzed for HPV DNA by the multiplex polymerase chain reaction method, where 1195 specimens were positive for cervical smear, except adenomatous lesions.
Result.
HPV genotypes were detected in 9.5% of NILM and 72.2% of ASC-US or more cervical lesions.
In positive cervical smears, HPV genotypes were HPV 52 at 26.6%, HPV 16 at 25.2%, HPV 58 at 21.8%, and HPV 18 at 7.1%.
Most patients infected with HPV 16 were between 20–29 years old, decreasing with age thereafter.
As for HPV 52 and 58, although the detection rate was high in 30- to 39-year-olds, it also was significant in the 50s and 60s age groups.
Conclusion.
In Japan, as a cause of abnormal cervical cytology, HPV52 and 58 are detected frequently in addition to HPV 16.
In older age groups, HPV 52 and 58 detection rates were higher than that observed for HPV 16.
After widespread current HPV vaccination, we still must be aware of HPV 52 and 58 infections.
American Psychological Association (APA)
Takehara, Kazuhiro& Toda, Tamaki& Nishimura, Toshinao& Sakane, Junichi& Kawakami, Yosuke& Mizunoe, Tomoya…[et al.]. 2011. Human Papillomavirus Types 52 and 58 Are Prevalent in Uterine Cervical Squamous Lesions from Japanese Women. Pathology Research International،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-457046
Modern Language Association (MLA)
Takehara, Kazuhiro…[et al.]. Human Papillomavirus Types 52 and 58 Are Prevalent in Uterine Cervical Squamous Lesions from Japanese Women. Pathology Research International No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-457046
American Medical Association (AMA)
Takehara, Kazuhiro& Toda, Tamaki& Nishimura, Toshinao& Sakane, Junichi& Kawakami, Yosuke& Mizunoe, Tomoya…[et al.]. Human Papillomavirus Types 52 and 58 Are Prevalent in Uterine Cervical Squamous Lesions from Japanese Women. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-457046
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457046