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A Review on the Anti-Inflammatory Activity of Pomegranate in the Gastrointestinal Tract
Joint Authors
Dell'Agli, Mario
Colombo, Elisa
Sangiovanni, Enrico
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Several biological activities of pomegranate have been widely described in the literature, but the anti-inflammatory effect in the gastrointestinal tract has not been reviewed till now.
The aim of the present paper is to summarize the evidence for or against the efficacy of pomegranate for coping with inflammatory conditions of the gastro-intestinal tract.
The paper has been organized in three parts: (1) the first one is devoted to the modifications of pomegranate active compounds in the gastro-intestinal tract; (2) the second one considering the literature regarding the anti-inflammatory effect of pomegranate at gastric level; (3) the third part considers the anti-inflammatory effect of pomegranate in the gut.
In vivo studies performed on the whole fruit or juice, peel, and flowers demonstrate antiulcer effect in a variety of animal models.
Ellagic acid was the main responsible for this effect, although other individual ellagitannins could contribute to the biological activity of the mixture.
Different preparations of pomegranate, including extracts from peels, flowers, seeds, and juice, show a significant anti-inflammatory activity in the gut.
No clinical studies have been found, thus suggesting that future clinical studies are necessary to clarify the beneficial effects of pomegranate in the gastrointestinal tract.
American Psychological Association (APA)
Colombo, Elisa& Sangiovanni, Enrico& Dell'Agli, Mario. 2013. A Review on the Anti-Inflammatory Activity of Pomegranate in the Gastrointestinal Tract. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-457067
Modern Language Association (MLA)
Colombo, Elisa…[et al.]. A Review on the Anti-Inflammatory Activity of Pomegranate in the Gastrointestinal Tract. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-457067
American Medical Association (AMA)
Colombo, Elisa& Sangiovanni, Enrico& Dell'Agli, Mario. A Review on the Anti-Inflammatory Activity of Pomegranate in the Gastrointestinal Tract. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-457067
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457067