Crystal Structure of Apraclonidine Hydrochloride
Author
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-23
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Apraclonidine is used for the treatment of postsurgical elevated intraocular pressure.
The crystal structure of its hydrochloride, C9H10Cl2N4·HCl, was determined by X-ray analysis.
The crystal belongs to space group P21/n with the cell dimensions a=9.665(10), b=11.8624(14), c=10.5675(11) Å, and β=92.199(9)°.
The final R (all reflections) value is 0.053.
Apraclonidine has a more twisted structure than its related drug of clonidine.
The nitrogen atom bridging the two rings is protonated.
American Psychological Association (APA)
Hirayama, Noriaki. 2013. Crystal Structure of Apraclonidine Hydrochloride. Journal of Crystallography،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-457327
Modern Language Association (MLA)
Hirayama, Noriaki. Crystal Structure of Apraclonidine Hydrochloride. Journal of Crystallography No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-457327
American Medical Association (AMA)
Hirayama, Noriaki. Crystal Structure of Apraclonidine Hydrochloride. Journal of Crystallography. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-457327
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457327
