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Synchronous and Metachronous Breast Malignancies : A Cross-Sectional Retrospective Study and Review of the Literature
Joint Authors
Minucci, Antonio
Caponnetto, Filippo
Bertozzi, Serena
Gentile, Giuliana
Bernardi, Sergio
Londero, Ambrogio P.
Angione, Vito
Dri, Cinzia
Petri, Roberto
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-27
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
There is increasing interest in patients with metachronous (MBC) and synchronous breast cancer (SBC).
The objective of this study was to evaluate the occurrence and outcome of MBCs and SBCs.
Methods.
A retrospective study on women operated in our department for breast cancer between 2002 and 2005 was carried out.
Patients were divided into three groups: women with MBC, SBC, and unilateral breast cancer (UBC).
Moreover, we performed a meta-analysis of the English literature about multiple breast cancers between 2000 and 2011 taking into consideration their prevalence and overall survival (OS).
Results.
We identified 584 breast cancer patients: 16 women (3%) presented SBC and 40 MBC (7%, second cancer after 72-month follow-up IQR 40–145).
Although the meta-analysis showed significant OS differences between MBC or SBC and UBC, we did not observe any significant OS difference among the three groups of our population.
Anyway, we found a significant worse disease-free survival in MBC than UBC and a significant higher prevalence of radical surgery in MBC and SBC than UBC.
Conclusions.
Despite the low prevalence of MBC and SBC, the presence of a long time risk of MBC confirms the crucial role of ipsi- and contralateral mammographies in the postoperative follow-up.
American Psychological Association (APA)
Londero, Ambrogio P.& Bernardi, Sergio& Bertozzi, Serena& Angione, Vito& Gentile, Giuliana& Dri, Cinzia…[et al.]. 2014. Synchronous and Metachronous Breast Malignancies : A Cross-Sectional Retrospective Study and Review of the Literature. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-457419
Modern Language Association (MLA)
Londero, Ambrogio P.…[et al.]. Synchronous and Metachronous Breast Malignancies : A Cross-Sectional Retrospective Study and Review of the Literature. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-457419
American Medical Association (AMA)
Londero, Ambrogio P.& Bernardi, Sergio& Bertozzi, Serena& Angione, Vito& Gentile, Giuliana& Dri, Cinzia…[et al.]. Synchronous and Metachronous Breast Malignancies : A Cross-Sectional Retrospective Study and Review of the Literature. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-457419
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457419