Zolpidem in Progressive Supranuclear Palsy
Author
Source
Case Reports in Neurological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-2, 2 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-09
Country of Publication
Egypt
No. of Pages
2
Main Subjects
Abstract EN
Progressive supranuclear palsy (PSP) is a progressive neurodegenerative disorder, characterized by motor symptoms, postural instability, personality changes, and cognitive impairment.
There is no effective treatment for this disorder.
Reduced neurotransmission of GABA in the striatum and globus pallidus may contribute to the symptoms of motor and cognitive symptoms seen in PSP.
Zolpidem is a GABA agonist of the benzodiazepine subreceptor BZ1.
Here a nondiabetic, normotensive case of PSP is (Progressive Supranuclear Palsy) described, which showed improvement in swallowing, speech, and gaze paresis after zolpidem therapy and possible mechanism of actions are discussed.
However, more trials are needed with large number of patients to confirm the effectiveness of zolpidem in progressive supranuclear palsy.
American Psychological Association (APA)
Dash, Sandip K.. 2013. Zolpidem in Progressive Supranuclear Palsy. Case Reports in Neurological Medicine،Vol. 2013, no. 2013, pp.1-2.
https://search.emarefa.net/detail/BIM-457440
Modern Language Association (MLA)
Dash, Sandip K.. Zolpidem in Progressive Supranuclear Palsy. Case Reports in Neurological Medicine No. 2013 (2013), pp.1-2.
https://search.emarefa.net/detail/BIM-457440
American Medical Association (AMA)
Dash, Sandip K.. Zolpidem in Progressive Supranuclear Palsy. Case Reports in Neurological Medicine. 2013. Vol. 2013, no. 2013, pp.1-2.
https://search.emarefa.net/detail/BIM-457440
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457440