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Cardiovascular Prevention of Cognitive Decline
Joint Authors
Rivera, Sofia
Gesquière-Dando, Aude
Monsuez, Jean-Jacques
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Midlife cardiovascular risk factors, including diabetes, hypertension, dyslipemia, and an unhealthy lifestyle, have been linked to subsequent incidence, delay of onset, and progression rate of Alzheimer disease and vascular dementia.
Conversely, optimal treatment of cardiovascular risk factors prevents and slows down age-related cognitive disorders.
The impact of antihypertensive therapy on cognitive outcome in patients with hypertension was assessed in large trials which demonstrated a reduction in progression of MRI white matter hyperintensities, in cognitive decline and in incidence of dementia.
Large-scale database correlated statin use and reduction in the incidence of dementia, mainly in patients with documented atherosclerosis, but clinical trials failed to reach similar conclusions.
Whether a multitargeted intervention would substantially improve protection, quality of life, and reduce medical cost expenditures in patients with lower risk profile has not been ascertained.
This would require appropriately designed trials targeting large populations and focusing on cognitive decline as a primary outcome endpoint.
American Psychological Association (APA)
Monsuez, Jean-Jacques& Gesquière-Dando, Aude& Rivera, Sofia. 2011. Cardiovascular Prevention of Cognitive Decline. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-457450
Modern Language Association (MLA)
Monsuez, Jean-Jacques…[et al.]. Cardiovascular Prevention of Cognitive Decline. Cardiology Research and Practice No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-457450
American Medical Association (AMA)
Monsuez, Jean-Jacques& Gesquière-Dando, Aude& Rivera, Sofia. Cardiovascular Prevention of Cognitive Decline. Cardiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-457450
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457450