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Functional Topography of Human Corpus Callosum : An fMRI Mapping Study
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-14
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
The concept of a topographical map of the corpus callosum (CC) has emerged from human lesion studies and from electrophysiological and anatomical tracing investigations in other mammals.
Over the last few years a rising number of researchers have been reporting functional magnetic resonance imaging (fMRI) activation in white matter, particularly the CC.
In this study the scope for describing CC topography with fMRI was explored by evoking activation through simple sensory stimulation and motor tasks.
We reviewed our published and unpublished fMRI and diffusion tensor imaging data on the cortical representation of tactile, gustatory, auditory, and visual sensitivity and of motor activation, obtained in 36 normal volunteers and in 6 patients with partial callosotomy.
Activation foci were consistently detected in discrete CC regions: anterior (taste stimuli), central (motor tasks), central and posterior (tactile stimuli), and splenium (auditory and visual stimuli).
Reconstruction of callosal fibers connecting activated primary gustatory, motor, somatosensory, auditory, and visual cortices by diffusion tensor tracking showed bundles crossing, respectively, through the genu, anterior and posterior body, and splenium, at sites harboring fMRI foci.
These data confirm that the CC commissure has a topographical organization and demonstrate that its functional topography can be explored with fMRI.
American Psychological Association (APA)
Fabri, Mara& Polonara, Gabriele. 2013. Functional Topography of Human Corpus Callosum : An fMRI Mapping Study. Neural Plasticity،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-457469
Modern Language Association (MLA)
Fabri, Mara& Polonara, Gabriele. Functional Topography of Human Corpus Callosum : An fMRI Mapping Study. Neural Plasticity No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-457469
American Medical Association (AMA)
Fabri, Mara& Polonara, Gabriele. Functional Topography of Human Corpus Callosum : An fMRI Mapping Study. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-457469
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457469