Asthma Control and Its Relationship with Obstructive Sleep Apnea (OSA) in Older Adults
Joint Authors
Consens, Flavia B.
Teodorescu, Mihaela
Fedie, Jessica E.
Chervin, Ronald D.
Polomis, David A.
Gangnon, Ronald E.
Teodorescu, Mihai C.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-06
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background/Objectives.
Asthma in older individuals is poorly understood.
We aimed to characterize the older asthma phenotype and test its association with obstructive sleep apnea (OSA).
Design.
Cross-sectional.
Setting.
Pulmonary and Asthma/Allergy clinics.
Participants.
659 asthma subjects aged 18–59 years (younger) and 154 aged 60–75 (older).
Measurements.
Sleep Apnea scale of Sleep Disorders Questionnaire (SA-SDQ), asthma severity step (1–4, severe if step 3 or 4), established OSA diagnosis, continuous positive airway pressure (CPAP) use, and comorbidities.
Results.
Older versus younger had worse control, as assessed by asthma step, lung function, and inhaled corticosteroid use.
Among older subjects, after controlling for known asthma aggravators, OSA diagnosis was the only factor robustly associated with severe asthma: on average, OSA was associated with nearly 7 times greater likelihood of severe asthma in an older individual (OR=6.67).
This relationship was of greater magnitude than in younger subjects (OR=2.16).
CPAP use attenuated the likelihood of severe asthma in older subjects by 91% (P=0.005), much more than in the younger asthmatics.
Conclusion.
Diagnosed OSA increases the risk for worse asthma control in older patients, while CPAP therapy may have greater impact on asthma outcomes.
Unrecognized OSA may be a reason for poor asthma control, particularly among older patients.
American Psychological Association (APA)
Teodorescu, Mihaela& Polomis, David A.& Gangnon, Ronald E.& Fedie, Jessica E.& Consens, Flavia B.& Chervin, Ronald D.…[et al.]. 2013. Asthma Control and Its Relationship with Obstructive Sleep Apnea (OSA) in Older Adults. Sleep Disorders،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-457500
Modern Language Association (MLA)
Teodorescu, Mihaela…[et al.]. Asthma Control and Its Relationship with Obstructive Sleep Apnea (OSA) in Older Adults. Sleep Disorders No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-457500
American Medical Association (AMA)
Teodorescu, Mihaela& Polomis, David A.& Gangnon, Ronald E.& Fedie, Jessica E.& Consens, Flavia B.& Chervin, Ronald D.…[et al.]. Asthma Control and Its Relationship with Obstructive Sleep Apnea (OSA) in Older Adults. Sleep Disorders. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-457500
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457500