A Novel Potentiometric Sensor for Determination of Neurotoxin β-N-Oxalyl-L-α, β-Diaminopropionic Acid

Abstract EN

A novel potentiometric sensor based on ionophore (Cd(NH2CH2CH2OCH2CH2OCH2CH2NH2)Ag3(CN)5) for the determination of β-N-oxalyl-l-α, β-diaminopropionic acid (ODAP) is developed.

The ODAP-selective membrane sensor demonstrates high sensitivity and short response time.

The detection limit of the ODAP-selective membrane sensor is about 2×10-6 mol L-1 and the response time is shorter than 6 s.

The linear dynamic range of the ODAP-selective membrane sensor is between ODAP concentrations of 1.0×10-2 and 1×10-6 mol L-1.

The ODAP-selective membrane sensor exhibits good operational stability for at least one week in dry conditions at 4–6°C.

It has a reproducible and stable response during continuous work for at least 10 h with a relative standard deviation of 0.28% (n = 18).