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Body Mass and Fat Mass in Refractory Asthma : An Observational 1 Year Follow-Up Study
Joint Authors
Bafadhel, Mona
Singapuri, Amisha
Monteiro, William
Bradding, Peter H.
Green, Ruth H.
Pavord, Ian D.
Brightling, Christopher E.
Wardlaw, Andrew J.
Terry, Sarah
Hargadon, Beverley
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Asthma and obesity are common; however the impact of obesity upon asthma remains uncertain.
Objectives.
To assess relationships between obesity and fat mass with airway inflammation, lung function, and disease control in patients with refractory asthma.
Methods.
151 refractory asthma patients were characterised for measures of airway inflammation, lung function, Juniper asthma control questionnaire (JACQ), body mass index (BMI), and fat mass index (FMI) derived from dual energy X-ray absorptiometry.
Patients were reassessed over 12 months.
Results.
74% of patients had an elevated BMI.
BMI and FMI correlated (r=0.9, P<.001).
FMI and JACQ correlated in men (r=0.3, P=.01).
After 12 months 23% lost weight.
Weight change over 12 months correlated with FEV1 change (r=−0.3, P=.03), but not with change in JACQ or exacerbations.
Conclusion.
Increased fat mass is common in refractory asthma and is associated with asthma symptom control in men.
Loss of weight is associated with improvement in lung function in refractory asthma.
American Psychological Association (APA)
Bafadhel, Mona& Singapuri, Amisha& Terry, Sarah& Hargadon, Beverley& Monteiro, William& Green, Ruth H.…[et al.]. 2010. Body Mass and Fat Mass in Refractory Asthma : An Observational 1 Year Follow-Up Study. Journal of Allergy،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-457534
Modern Language Association (MLA)
Bafadhel, Mona…[et al.]. Body Mass and Fat Mass in Refractory Asthma : An Observational 1 Year Follow-Up Study. Journal of Allergy No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-457534
American Medical Association (AMA)
Bafadhel, Mona& Singapuri, Amisha& Terry, Sarah& Hargadon, Beverley& Monteiro, William& Green, Ruth H.…[et al.]. Body Mass and Fat Mass in Refractory Asthma : An Observational 1 Year Follow-Up Study. Journal of Allergy. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-457534
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457534