![](/images/graphics-bg.png)
Metastatic Insulinoma Managed with Radiolabeled Somatostatin Analog
Joint Authors
Bacchi, Carlos E.
Costa, Ricardo
Almeida Filho, Paulo
Costa, Rubens
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Insulinoma is a rare pancreatic neuroendocrine tumor.
Overproduction of insulin and associated hypoglycemia are hallmark features of this disease.
Diagnosis can be made through demonstration of hypoglycemia and elevated plasma levels of insulin or C-Peptide.
Metastatic disease can be detected through computerized tomography (CT) scans, magnetic resonance imaging (MRI), and positron emission tomography (PET)/CT.
Somatostatin receptor scintigraphy can be used not only to document metastatic disease but also as a predictive marker of the benefit from therapy with radiolabeled somatostatin analog.
Unresectable metastatic insulinomas may present as a major therapeutic challenge for the treating physician.
When feasible, resection is the mainstay of treatment.
Prevention of hypoglycemia is a crucial goal of therapy for unresectable/metastatic tumors.
Diazoxide, hydrochlorothiazide, glucagon, and intravenous glucose infusions have been used for glycemic control yielding temporary and inconsistent results.
Sandostatin and its long-acting depot forms have occasionally been used in the treatment of Octreoscan-positive insulinomas.
Herein, we report a case of metastatic insulinoma with very difficult glycemic control successfully treated with the radiolabeled somatostatin analog lutetium (177LU).
American Psychological Association (APA)
Costa, Ricardo& Costa, Rubens& Bacchi, Carlos E.& Almeida Filho, Paulo. 2013. Metastatic Insulinoma Managed with Radiolabeled Somatostatin Analog. Case Reports in Endocrinology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-457565
Modern Language Association (MLA)
Costa, Ricardo…[et al.]. Metastatic Insulinoma Managed with Radiolabeled Somatostatin Analog. Case Reports in Endocrinology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-457565
American Medical Association (AMA)
Costa, Ricardo& Costa, Rubens& Bacchi, Carlos E.& Almeida Filho, Paulo. Metastatic Insulinoma Managed with Radiolabeled Somatostatin Analog. Case Reports in Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-457565
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457565