Possible Involvement of Tight Junctions, Extracellular Matrix and Nuclear Receptors in Epithelial Differentiation
Joint Authors
Satohisa, Seiro
Chiba, Hideki
Nishiura, Keisuke
Ichikawa-Tomikawa, Naoki
Sugimoto, Kotaro
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-17
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Tight junctions are intercellular junctions localized at the most apical end of the lateral plasma membrane.
They consist of four kinds of transmembrane proteins (occludin, claudins, junctional adhesion molecules, and tricellulin) and huge numbers of scaffolding proteins and contribute to the paracellular barrier and fence function.
The mutation and deletion of these proteins impair the functions of tight junctions and cause various human diseases.
In this paper, we provide an overview of recent studies on transmembrane proteins of tight junctions and highlight the functional significance of tight junctions, extracellular matrix, and nuclear receptors in epithelial differentiation.
American Psychological Association (APA)
Ichikawa-Tomikawa, Naoki& Sugimoto, Kotaro& Satohisa, Seiro& Nishiura, Keisuke& Chiba, Hideki. 2011. Possible Involvement of Tight Junctions, Extracellular Matrix and Nuclear Receptors in Epithelial Differentiation. Journal of Biomedicine and Biotechnology،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-457630
Modern Language Association (MLA)
Ichikawa-Tomikawa, Naoki…[et al.]. Possible Involvement of Tight Junctions, Extracellular Matrix and Nuclear Receptors in Epithelial Differentiation. Journal of Biomedicine and Biotechnology No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-457630
American Medical Association (AMA)
Ichikawa-Tomikawa, Naoki& Sugimoto, Kotaro& Satohisa, Seiro& Nishiura, Keisuke& Chiba, Hideki. Possible Involvement of Tight Junctions, Extracellular Matrix and Nuclear Receptors in Epithelial Differentiation. Journal of Biomedicine and Biotechnology. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-457630
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457630