Milan Criteria and UCSF Criteria : A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States
Joint Authors
Arrington, Amanda K.
Nissen, Nicholas N.
McKenzie, Shaun
Ding, Michelle
Lee, Wendy
Mailey, Brian
Colquhoun, Steven D.
Kim, Joseph
Patel, Supriya S.
Artinyan, Avo
Source
International Journal of Hepatology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The application of orthotopic liver transplantation (OLT) for patients with hepatocellular cancer (HCC) necessitates highly selective criteria to maximize survival and to optimize allocation of a scarce resource.
The objective of this study was to compare the outcomes of OLT for HCC in patients transplanted under Milan and UCSF criteria.
The United Network of Organ Sharing (UNOS) database was queried for patients who had undergone OLT for HCC from 2002 to 2007, and 1,972 patients (Milan criteria, n=1,913; UCSF criteria, n=59) were identified.
Patients were stratified by pretransplant criteria (Milan versus UCSF), and clinical and pathologic factors and overall survival were compared.
There were no differences in age, gender, diabetes mellitus, body mass index, and hepatitis B, or C status between the two groups.
Overall survival was similar between the Milan and UCSF cohorts (1-, 2-, 3-, and 4-year survival rates: 88%, 81%, 76%, and 72% versus 91%, 80%, 68% and 51%, respectively, P=0.21).
Although the number of patients within UCSF criteria was small, our results nevertheless suggest that patients with HCC may have equivalent survival when transplanted under Milan and UCSF criteria.
Long-term followup may better determine whether UCSF criteria should be widely adopted.
American Psychological Association (APA)
Patel, Supriya S.& Arrington, Amanda K.& McKenzie, Shaun& Mailey, Brian& Ding, Michelle& Lee, Wendy…[et al.]. 2012. Milan Criteria and UCSF Criteria : A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States. International Journal of Hepatology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-457663
Modern Language Association (MLA)
Patel, Supriya S.…[et al.]. Milan Criteria and UCSF Criteria : A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States. International Journal of Hepatology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-457663
American Medical Association (AMA)
Patel, Supriya S.& Arrington, Amanda K.& McKenzie, Shaun& Mailey, Brian& Ding, Michelle& Lee, Wendy…[et al.]. Milan Criteria and UCSF Criteria : A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States. International Journal of Hepatology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-457663
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457663