Computational Laser Spectroscopy in a Biological Tissue

Abstract EN

We present a numerical spectroscopic study of visible and infrared laser radiation in a biological tissue.

We derive a solution of a general two-dimensional time dependent radiative transfer equation in a tissue-like medium.

The used model is suitable for many situations especially when the external source is time-dependent or continuous.

We use a control volume-discrete ordinate method associated with an implicit three-level second-order time differencing scheme.

We consider a very thin rectangular biological-tissue-like medium submitted to a visible or a near infrared light sources.

The RTE is solved for a set of different wavelength source.

All sources are assumed to be monochromatic and collimated.

The energetic fluence rate is computed at a set of detector points on the boundaries.

According to the source type, we investigate either the steady-state or transient response of the medium.

The used model is validated in the case of a heterogeneous tissue-like medium using referencing experimental results from the literature.

Also, the developed model is used to study changes on transmitted light in a rat-liver tissue-like medium.

Optical properties depend on the source wavelength and they are taken from the literature.

In particular, light-transmission in the medium is studied for continuous wave and for short pulse.