An Optically Controlled 3D Cell Culturing System
Joint Authors
Ohta, Aaron T.
Hu, Wenqi
Ishii, Kelly S.
Namekar, Swapnil A.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
A novel 3D cell culture system was developed and tested.
The cell culture device consists of a microfluidic chamber on an optically absorbing substrate.
Cells are suspended in a thermoresponsive hydrogel solution, and optical patterns are utilized to heat the solution, producing localized hydrogel formation around cells of interest.
The hydrogel traps only the desired cells in place while also serving as a biocompatible scaffold for supporting the cultivation of cells in 3D.
This is demonstrated with the trapping of MDCK II and HeLa cells.
The light intensity from the optically induced hydrogel formation does not significantly affect cell viability.
American Psychological Association (APA)
Ishii, Kelly S.& Hu, Wenqi& Namekar, Swapnil A.& Ohta, Aaron T.. 2011. An Optically Controlled 3D Cell Culturing System. Advances in OptoElectronics،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-457716
Modern Language Association (MLA)
Ishii, Kelly S.…[et al.]. An Optically Controlled 3D Cell Culturing System. Advances in OptoElectronics No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-457716
American Medical Association (AMA)
Ishii, Kelly S.& Hu, Wenqi& Namekar, Swapnil A.& Ohta, Aaron T.. An Optically Controlled 3D Cell Culturing System. Advances in OptoElectronics. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-457716
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457716