An Optically Controlled 3D Cell Culturing System

Joint Authors

Ohta, Aaron T.
Hu, Wenqi
Ishii, Kelly S.
Namekar, Swapnil A.

Source

Advances in OptoElectronics

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-12-13

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Electronic engineering

Abstract EN

A novel 3D cell culture system was developed and tested.

The cell culture device consists of a microfluidic chamber on an optically absorbing substrate.

Cells are suspended in a thermoresponsive hydrogel solution, and optical patterns are utilized to heat the solution, producing localized hydrogel formation around cells of interest.

The hydrogel traps only the desired cells in place while also serving as a biocompatible scaffold for supporting the cultivation of cells in 3D.

This is demonstrated with the trapping of MDCK II and HeLa cells.

The light intensity from the optically induced hydrogel formation does not significantly affect cell viability.

American Psychological Association (APA)

Ishii, Kelly S.& Hu, Wenqi& Namekar, Swapnil A.& Ohta, Aaron T.. 2011. An Optically Controlled 3D Cell Culturing System. Advances in OptoElectronics،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-457716

Modern Language Association (MLA)

Ishii, Kelly S.…[et al.]. An Optically Controlled 3D Cell Culturing System. Advances in OptoElectronics No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-457716

American Medical Association (AMA)

Ishii, Kelly S.& Hu, Wenqi& Namekar, Swapnil A.& Ohta, Aaron T.. An Optically Controlled 3D Cell Culturing System. Advances in OptoElectronics. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-457716

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-457716