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The Interaction of Plasma Sialylated and Desialylated Lipoproteins with Collagen from the Intima and Media of Uninvolved and Atherosclerotic Human Aorta
Joint Authors
Suprun, Igor V.
Orekhov, Alexander N.
Feoktistov, Alexander S.
Sobenin, Igor A.
Melnichenko, Alexandra A.
Karagodin, Vasiliy P.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We have evaluated the binding of sialylated and desialylated lipoproteins to collagen isolated from the proteoglycan and musculoelastic layers of intima and media of uninvolved human aorta and atherosclerotic lesions.
Comparing various collagen preparations from the uninvolved intima-media, the binding of sialylated apoB-containing lipoproteins was best to collagen from the intimal PG-rich layer.
Binding of sialylated apoB-containing lipoproteins to collagen from this layer of fatty streak and fibroatheroma was 1.4- and 3.1-fold lower, respectively, in comparison with normal intima.
Desialylated VLDL versus sialylated one exhibited a greater binding (1.4- to 3.0-fold) to all the collagen preparations examined.
Desialylated IDL and LDL showed a higher binding than sialylated ones when collagen from the intimal layers of fibroatheroma was used.
Binding of desialylated HDL to collagen from the intimal PG-rich layer of normal tissue, initial lesion, and fatty streak was 1.2- to 2.0-fold higher compared with sialylated HDL.
American Psychological Association (APA)
Sobenin, Igor A.& Suprun, Igor V.& Karagodin, Vasiliy P.& Feoktistov, Alexander S.& Melnichenko, Alexandra A.& Orekhov, Alexander N.. 2011. The Interaction of Plasma Sialylated and Desialylated Lipoproteins with Collagen from the Intima and Media of Uninvolved and Atherosclerotic Human Aorta. Journal of Lipids،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-457744
Modern Language Association (MLA)
Sobenin, Igor A.…[et al.]. The Interaction of Plasma Sialylated and Desialylated Lipoproteins with Collagen from the Intima and Media of Uninvolved and Atherosclerotic Human Aorta. Journal of Lipids No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-457744
American Medical Association (AMA)
Sobenin, Igor A.& Suprun, Igor V.& Karagodin, Vasiliy P.& Feoktistov, Alexander S.& Melnichenko, Alexandra A.& Orekhov, Alexander N.. The Interaction of Plasma Sialylated and Desialylated Lipoproteins with Collagen from the Intima and Media of Uninvolved and Atherosclerotic Human Aorta. Journal of Lipids. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-457744
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457744