Serum Iron Status of Under-Five Children with Sickle Cell Anaemia in Lagos, Nigeria
Joint Authors
Njokanma, Olisamedua Fidelis
Akodu, Samuel Olufemi
Diaku-Akinwumi, I. N.
Kehinde, Omolara Adeolu
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Iron status in patients with sickle cell anaemia is a matter of continuing investigation.
Objective.
This paper aims to determine the serum iron status of under-five, sickle cell anaemia patients.
Methods.
The study spanned from December 2009 to February 2010 at the Consultant Outpatient Clinics involving 97 HbSS subjects and 97 age- and sex-matched HbAA controls.
Biochemical iron status was assayed in subjects and controls.
Results.
Age range of the children was seven months to five years, with a mean of 30.6 (±15.97) months.
Irrespective of gender, mean serum iron values were higher in HbAA controls than their HbSS counterparts but the observed difference was not significant (P=0.299 and 0.111, resp.).
The mean total iron binding capacity values of males and females were also not significantly different for sickle cell anaemia subjects and controls (P>0.05).
Males and females with HbAA had significantly lower serum ferritin when compared with their HbSS counterparts.
Irrespective of gender, mean transferrin saturation was lower in HbSS subjects but the difference was not statistically significant (P>0.05).
Conclusion.
Children with sickle cell anaemia have higher serum ferritin than controls, implying relatively higher iron content in the reticuloendothelial cells.
American Psychological Association (APA)
Akodu, Samuel Olufemi& Diaku-Akinwumi, I. N.& Kehinde, Omolara Adeolu& Njokanma, Olisamedua Fidelis. 2013. Serum Iron Status of Under-Five Children with Sickle Cell Anaemia in Lagos, Nigeria. Anemia،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-457790
Modern Language Association (MLA)
Akodu, Samuel Olufemi…[et al.]. Serum Iron Status of Under-Five Children with Sickle Cell Anaemia in Lagos, Nigeria. Anemia No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-457790
American Medical Association (AMA)
Akodu, Samuel Olufemi& Diaku-Akinwumi, I. N.& Kehinde, Omolara Adeolu& Njokanma, Olisamedua Fidelis. Serum Iron Status of Under-Five Children with Sickle Cell Anaemia in Lagos, Nigeria. Anemia. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-457790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457790