Narrow Band Imaging with Magnification Can Pick Up Esophageal Squamous Cell Carcinoma More Efficiently Than Lugol Chromoendoscopy in Patients after Chemoradiotherapy
Joint Authors
Asada-Hirayama, Itsuko
Konno-Shimizu, Maki
Niimi, Keiko
Koike, Kazuhiko
Minatsuki, Chihiro
Kodashima, Shinya
Yamamichi, Nobutake
Ono, Satoshi
Mikami-Matsuda, Rie
Nakayama, Chiemi
Mochizuki, Satoshi
Fujishiro, Mitsuhiro
Takahashi, Yu
Source
Diagnostic and Therapeutic Endoscopy
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
Little is known about the usefulness of narrow band imaging (NBI) for surveillance of patients after chemoradiotherapy for esophageal neoplasia.
Its usefulness in detecting esophageal squamous cell carcinoma (SCC) or high-grade intraepithelial neoplasia (HGIN) in these patients was retrospectively compared to Lugol chromoendoscopy.
Patients and Methods.
We assessed the diagnostic ability of NBI with magnification based on the biopsy specimens obtained from iodine-unstained lesions.
Seventy-two iodine-unstained lesions were biopsied and consecutively enrolled for this study.
The lesions were divided into NBI positive and NBI negative.
Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of NBI with magnification and PPV of Lugol chromoendoscopy was calculated using histological assessment as a gold standard.
Results.
Forty-six endoscopic examinations using NBI with magnification followed by Lugol chromoendoscopy were performed to 28 patients.
The prevalence of SCC and HGIN was 21.4%.
Sensitivity, specificity, PPV, NPV, and accuracy of NBI were 100.0%, 98.5%, 85.7%, 100%, and 98.6%, respectively.
On the contrary, PPV of Lugol chromoendoscopy were 8.3%.
Compared to Lugol chromoendoscopy, NBI with magnification showed equal sensitivity and significantly higher PPV (P<0.0001).
Conclusion.
NBI with magnification would be able to pick up esophageal neoplasia more efficiently than Lugol chromoendoscopy in patients after chemoradiotherapy.
American Psychological Association (APA)
Asada-Hirayama, Itsuko& Kodashima, Shinya& Fujishiro, Mitsuhiro& Ono, Satoshi& Niimi, Keiko& Mochizuki, Satoshi…[et al.]. 2013. Narrow Band Imaging with Magnification Can Pick Up Esophageal Squamous Cell Carcinoma More Efficiently Than Lugol Chromoendoscopy in Patients after Chemoradiotherapy. Diagnostic and Therapeutic Endoscopy،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-457868
Modern Language Association (MLA)
Asada-Hirayama, Itsuko…[et al.]. Narrow Band Imaging with Magnification Can Pick Up Esophageal Squamous Cell Carcinoma More Efficiently Than Lugol Chromoendoscopy in Patients after Chemoradiotherapy. Diagnostic and Therapeutic Endoscopy No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-457868
American Medical Association (AMA)
Asada-Hirayama, Itsuko& Kodashima, Shinya& Fujishiro, Mitsuhiro& Ono, Satoshi& Niimi, Keiko& Mochizuki, Satoshi…[et al.]. Narrow Band Imaging with Magnification Can Pick Up Esophageal Squamous Cell Carcinoma More Efficiently Than Lugol Chromoendoscopy in Patients after Chemoradiotherapy. Diagnostic and Therapeutic Endoscopy. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-457868
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457868