Targeting Insulin and Insulin-Like Growth Factor Pathways in Epithelial Ovarian Cancer
Joint Authors
Beauchamp, Marie-Claude
Knafo, Ariane
Gotlieb, Walter H.
Yasmeen, Amber
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Ovarian cancer is the most lethal of all gynecological malignancies, due in part to the diagnosis at an advanced stage caused by the lack of specific signs and symptoms and the absence of reliable tests for screening and early detection.
Most patients will respond initially to treatment but about 70% of them will suffer a recurrence.
Therefore, new therapeutic modalities are urgently needed to overcome chemoresistance observed in ovarian cancer patients.
Evidence accumulates suggesting that the insulin/insulin growth factor (IGF) pathways could act as a good therapeutic target in several cancers, including ovarian cancer.
In this paper, we will focus on the role of insulin/IGF in ovarian cancer tumorigenesis and treatment.
American Psychological Association (APA)
Beauchamp, Marie-Claude& Yasmeen, Amber& Knafo, Ariane& Gotlieb, Walter H.. 2010. Targeting Insulin and Insulin-Like Growth Factor Pathways in Epithelial Ovarian Cancer. Journal of Oncology،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-457929
Modern Language Association (MLA)
Beauchamp, Marie-Claude…[et al.]. Targeting Insulin and Insulin-Like Growth Factor Pathways in Epithelial Ovarian Cancer. Journal of Oncology No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-457929
American Medical Association (AMA)
Beauchamp, Marie-Claude& Yasmeen, Amber& Knafo, Ariane& Gotlieb, Walter H.. Targeting Insulin and Insulin-Like Growth Factor Pathways in Epithelial Ovarian Cancer. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-457929
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457929