Current Perspectives in NSAID-Induced Gastropathy
Joint Authors
Shukla, Prakash Kumar
Kaur, Punit
Gautam, Lovely
Sharma, Sujata
Sinha, Mau
Singh, Tej P.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-12
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most highly prescribed drugs in the world.
Their analgesic, anti-inflammatory, and antipyretic actions may be beneficial; however, they are associated with severe side effects including gastrointestinal injury and peptic ulceration.
Though several approaches for limiting these side effects have been adopted, like the use of COX-2 specific drugs, comedication of acid suppressants like proton pump inhibitors and prostaglandin analogs, these alternatives have limitations in terms of efficacy and side effects.
In this paper, the mechanism of action of NSAIDs and their critical gastrointestinal complications have been reviewed.
This paper also provides the information on different preventive measures prescribed to minimize such adverse effects and analyses the new suggested strategies for development of novel drugs to maintain the anti-inflammatory functions of NSAIDs along with effective gastrointestinal protection.
American Psychological Association (APA)
Sinha, Mau& Gautam, Lovely& Shukla, Prakash Kumar& Kaur, Punit& Sharma, Sujata& Singh, Tej P.. 2013. Current Perspectives in NSAID-Induced Gastropathy. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-458059
Modern Language Association (MLA)
Sinha, Mau…[et al.]. Current Perspectives in NSAID-Induced Gastropathy. Mediators of Inflammation No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-458059
American Medical Association (AMA)
Sinha, Mau& Gautam, Lovely& Shukla, Prakash Kumar& Kaur, Punit& Sharma, Sujata& Singh, Tej P.. Current Perspectives in NSAID-Induced Gastropathy. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-458059
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458059