![](/images/graphics-bg.png)
Human Aqueous Humor Levels of TGF-β2 : Relationship with Axial Length
Joint Authors
Jia, Yan
Hu, Dan-Ning
Zhou, Jibo
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To analyze the relationship between transforming growth factor-beta 2 (TGF-β2) levels in the anterior chamber aqueous humor and axial length of patients with myopia.
Methods.
TGF-β2 was measured with the Luminex xMAP Technology by using commercially available Milliplex xMAP Kits.
Sixty-five aqueous humor samples were collected during cataract or clear lens extraction surgery and TGF-β2 levels in these specimens were analyzed.
According to the axial length, the samples were divided into three groups: A (AL ≤24 mm), B (24~29 mm), and C (AL ≥ 29 mm).
Results.
Aqueous humor samples were analyzed from subjects with an average age of 67.0 ± 11.7 years.
Mean TGF-β2 concentration of all aqueous samples was 422.2 ± 258.8 pg/mL.
TGF-β2 concentration in group C (543 ± 317 pg/mL) was significantly greater than that in group A (390 ± 212 pg/mL) and group B (337 ± 217 pg/mL).
The concentration of TGF-β2 was positively correlated with axial length (r = 0.308, P = 0.013).
Conclusions.
TGF-β2 is likely to be acting as a critical factor in axial elongation and development of myopia.
American Psychological Association (APA)
Jia, Yan& Hu, Dan-Ning& Zhou, Jibo. 2014. Human Aqueous Humor Levels of TGF-β2 : Relationship with Axial Length. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-458106
Modern Language Association (MLA)
Jia, Yan…[et al.]. Human Aqueous Humor Levels of TGF-β2 : Relationship with Axial Length. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-458106
American Medical Association (AMA)
Jia, Yan& Hu, Dan-Ning& Zhou, Jibo. Human Aqueous Humor Levels of TGF-β2 : Relationship with Axial Length. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-458106
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458106