Characterisation of Flavonoid Aglycones by Negative Ion Chip-Based Nanospray Tandem Mass Spectrometry
Joint Authors
Lopes, Norberto Peporine
Gates, Paul Jonathan
Source
International Journal of Analytical Chemistry
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Flavonoids are one of the most important classes of natural products having a wide variety of biological activities.
There is wide interest in a range of medical and dietary applications, and having a rapid, reliable method for structural elucidation is essential.
In this study a range of flavonoid standards are investigated by chip-based negative ion nanospray mass spectrometry.
It was found that the different classes of flavonoid studied have a combination of distinct neutral losses from the precursor ion [M-H]− along with characteristic low-mass ions.
By looking only for this distinct pattern of product ions, it is possible to determine the class of flavonoid directly.
This methodology is tested here by the analysis of a green tea extract, where the expected flavonoids were readily identified, along with quercetin, which is shown to be present at only about 2% of the most intense ion in the spectrum.
American Psychological Association (APA)
Gates, Paul Jonathan& Lopes, Norberto Peporine. 2012. Characterisation of Flavonoid Aglycones by Negative Ion Chip-Based Nanospray Tandem Mass Spectrometry. International Journal of Analytical Chemistry،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-458162
Modern Language Association (MLA)
Gates, Paul Jonathan& Lopes, Norberto Peporine. Characterisation of Flavonoid Aglycones by Negative Ion Chip-Based Nanospray Tandem Mass Spectrometry. International Journal of Analytical Chemistry No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-458162
American Medical Association (AMA)
Gates, Paul Jonathan& Lopes, Norberto Peporine. Characterisation of Flavonoid Aglycones by Negative Ion Chip-Based Nanospray Tandem Mass Spectrometry. International Journal of Analytical Chemistry. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-458162
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458162