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Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders
Joint Authors
Liao, Mei-Hsiu
Shen, Lie-Hang
Tseng, Yu-Chin
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-10
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Dopamine is the most intensely studied monoaminergic neurotransmitter.
Dopaminergic neurotransmission plays an important role in regulating several aspects of basic brain function, including motor, behavior, motivation, and working memory.
To date, there are numerous positron emission tomography (PET) and single photon emission computed tomography (SPECT) radiotracers available for targeting different steps in the process of dopaminergic neurotransmission, which permits us to quantify dopaminergic activity in the living human brain.
Degeneration of the nigrostriatal dopamine system causes Parkinson’s disease (PD) and related Parkinsonism.
Dopamine is the neurotransmitter that has been classically associated with the reinforcing effects of drug abuse.
Abnormalities within the dopamine system in the brain are involved in the pathophysiology of attention deficit hyperactivity disorder (ADHD).
Dopamine receptors play an important role in schizophrenia and the effect of neuroleptics is through blockage of dopamine D2 receptors.
This review will concentrate on the radiotracers that have been developed for imaging dopaminergic neurons, describe the clinical aspects in the assessment of neuropsychiatric disorders, and suggest future directions in the diagnosis and management of such disorders.
American Psychological Association (APA)
Shen, Lie-Hang& Liao, Mei-Hsiu& Tseng, Yu-Chin. 2012. Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-458173
Modern Language Association (MLA)
Shen, Lie-Hang…[et al.]. Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-458173
American Medical Association (AMA)
Shen, Lie-Hang& Liao, Mei-Hsiu& Tseng, Yu-Chin. Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-458173
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458173