Similarity and Diversity in Macrophage Activation by Nematodes, Trematodes, and Cestodes
Joint Authors
Allen, Judith E.
Jenkins, Stephen J.
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-26
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
This review summarizes current knowledge of macrophages in helminth infections, with a focus not only on delineating the striking similarities in macrophage phenotype between diverse infections but also on highlighting the differences.
Findings from many different labs illustrate that macrophages in helminth infection can act as anti-parasite effectors but can also act as powerful immune suppressors.
The specific role for their alternative (Th2-mediated) activation in helminth killing or expulsion versus immune regulation remains to be determined.
Meanwhile, the rapid growth in knowledge of alternatively activated macrophages will require an even more expansive view of their potential functions to include repair of host tissue and regulation of host metabolism.
American Psychological Association (APA)
Jenkins, Stephen J.& Allen, Judith E.. 2010. Similarity and Diversity in Macrophage Activation by Nematodes, Trematodes, and Cestodes. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-14.
https://search.emarefa.net/detail/BIM-458473
Modern Language Association (MLA)
Jenkins, Stephen J.& Allen, Judith E.. Similarity and Diversity in Macrophage Activation by Nematodes, Trematodes, and Cestodes. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-14.
https://search.emarefa.net/detail/BIM-458473
American Medical Association (AMA)
Jenkins, Stephen J.& Allen, Judith E.. Similarity and Diversity in Macrophage Activation by Nematodes, Trematodes, and Cestodes. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-14.
https://search.emarefa.net/detail/BIM-458473
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458473