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Toxicity of Citrate-Capped Silver Nanoparticles in Common Carp (Cyprinus carpio)
Joint Authors
Kim, Kyungtae
Kim, Pilje
Lee, Jaewoo
Cho, Jaegu
Choi, Kyunghee
Seo, Youngrok
Lee, Byoungcheun
Duong, Cuong Ngoc
Yoon, Junheon
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Juvenile common carp (Cyprinus carpio) were used as a model to investigate acute toxicity and oxidative stress caused by silver nanoparticles (Ag-NPs).
The fish were exposed to different concentrations of Ag-NPs for 48 h and 96 h.
After exposure, antioxidant enzyme levels were measured, including glutathione-S-transferase (GST), superoxidase dismutase, and catalase (CAT).
Other biochemical parameters and histological abnormalities in different tissues (i.e., the liver, gills, and brain) were also examined.
The results showed that Ag-NPs agglomerated in freshwater used during the exposure experiments, with particle size remaining <100 nm.
Ag-NPs had no lethal effect on fish after 4 days of exposure.
Biochemical analysis showed that enzymatic activities in the brain of the fish exposed to 200 μg/L of Ag-NPs were significantly reduced.
Varied antioxidant enzyme activity was recorded in the liver and gills.
Varied antioxidant enzyme activity was recorded for CAT in the liver and GST in the gills of the fish.
However, the recovery rate of fish exposed to 200 μg/L of Ag-NPs was slower than when lower particle concentrations were used.
Other biochemical indices showed no significant difference, except for NH3 and blood urea nitrogen concentrations in fish exposed to 50 μg/L of Ag-NPs.
This study provides new evidence about the effects of nanoparticles on aquatic organisms.
American Psychological Association (APA)
Lee, Byoungcheun& Duong, Cuong Ngoc& Cho, Jaegu& Lee, Jaewoo& Kim, Kyungtae& Seo, Youngrok…[et al.]. 2012. Toxicity of Citrate-Capped Silver Nanoparticles in Common Carp (Cyprinus carpio). Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-458476
Modern Language Association (MLA)
Lee, Byoungcheun…[et al.]. Toxicity of Citrate-Capped Silver Nanoparticles in Common Carp (Cyprinus carpio). Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-458476
American Medical Association (AMA)
Lee, Byoungcheun& Duong, Cuong Ngoc& Cho, Jaegu& Lee, Jaewoo& Kim, Kyungtae& Seo, Youngrok…[et al.]. Toxicity of Citrate-Capped Silver Nanoparticles in Common Carp (Cyprinus carpio). Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-458476
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458476