Cost-Effectiveness of Catheter Ablation for Rhythm Control of Atrial Fibrillation
Joint Authors
Xie, Feng
Gaebel, Kathryn
O'Reilly, Daria
Assasi, Nazila
Blackhouse, Gord
Healey, Jeff S.
Campbell, Kaitryn
Goeree, Ron
Source
International Journal of Vascular Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-08
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
The objective of this study is to evaluate the cost-effectiveness of catheter ablation for rhythm control compared to antiarrhythmic drug (AAD) therapy in patients with atrial fibrillation (AF) who have previously failed on an AAD.
Methods.
An economic model was developed to compare (1) catheter ablation and (2) AAD (amiodarone 200 mg/day).
At the end of the initial 12 month phase of the model, patients are classified as being in normal sinus rhythm or with AF, based on data from a meta-analysis.
In the 5-year Markov phase of the model, patients are at risk of ischemic stroke each 3-month model cycle.
Results.
The model estimated that, compared to the AAD strategy, ablation had $8,539 higher costs, 0.033 fewer strokes, and 0.144 more QALYS over the 5-year time horizon.
The incremental cost per QALY of ablation compared to AAD was estimated to be $59,194.
The probability of ablation being cost-effective for willingness to pay thresholds of $50,000 and $100,000 was estimated to be 0.89 and 0.90, respectively.
Conclusion.
Based on current evidence, pulmonary vein ablation for treatment of AF is cost-effective if decision makers willingness to pay for a QALY is $59,194 or higher.
American Psychological Association (APA)
Blackhouse, Gord& Assasi, Nazila& Xie, Feng& Gaebel, Kathryn& Campbell, Kaitryn& Healey, Jeff S.…[et al.]. 2013. Cost-Effectiveness of Catheter Ablation for Rhythm Control of Atrial Fibrillation. International Journal of Vascular Medicine،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-458487
Modern Language Association (MLA)
Blackhouse, Gord…[et al.]. Cost-Effectiveness of Catheter Ablation for Rhythm Control of Atrial Fibrillation. International Journal of Vascular Medicine No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-458487
American Medical Association (AMA)
Blackhouse, Gord& Assasi, Nazila& Xie, Feng& Gaebel, Kathryn& Campbell, Kaitryn& Healey, Jeff S.…[et al.]. Cost-Effectiveness of Catheter Ablation for Rhythm Control of Atrial Fibrillation. International Journal of Vascular Medicine. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-458487
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458487